PPA1

Gene Name		pyrophosphatase (inorganic) 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Inorganic Diphosphatase Activity
	Biological Process	TRNA Aminoacylation For Protein Translation Phosphate-containing Compound Metabolic Process Gene Expression Diphosphate Metabolic Process
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: HSPB1 MTRNR2L1 SETDB1 SUMO4 TP53 UNC119 WIPI1
Entrez ID		5464
HPRD ID		01527
Ensembl ID		ENSG00000180817
Uniprot IDs		Q15181
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis ER-nucleus Signaling Pathway Response To Unfolded Protein Response To External Stimulus Negative Regulation Of Macromitophagy Negative Regulation Of Caveolin-mediated Endocytosis Oligodendrocyte Apoptotic Process Vesicle Targeting, Trans-Golgi To Endosome Cellular Response To Starvation Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Response To Endoplasmic Reticulum Stress Cytokinesis, Completion Of Separation Negative Regulation Of Helicase Activity Cellular Response To Nutrient Levels Response To Starvation Positive Regulation Of Phosphorylation Regulation Of Protein Metabolic Process Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Extracellular Stimulus Regulation Of Catalytic Activity Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Mitochondrial DNA Repair Regulation Of Caveolin-mediated Endocytosis Peptidyl-lysine Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Mitotic Cytokinetic Process Glial Cell Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Endothelial Cell Chemotaxis Oxidative Stress-induced Premature Senescence Protein Localization To Pre-autophagosomal Structure Histone H3-K9 Trimethylation ER Overload Response Homotypic Cell-cell Adhesion
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