NDFIP2

Description		Nedd4 family interacting protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Endosome Endoplasmic Reticulum Golgi Apparatus Endosome Membrane Membrane Multivesicular Body Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding WW Domain Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Vacuolar Transport Negative Regulation Of Gene Expression Metal Ion Transport Positive Regulation Of Protein Ubiquitination Negative Regulation Of Transporter Activity Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Protein Transport
Pathways
Drugs
Diseases
GWAS		Bullous pemphigoid ( 34011352) Leisure-time exercise behaviour (age-stratified) ( 30102679) Major depressive disorder ( 23377640) Metabolite levels ( 23823483) Pancreatic cancer ( 20686608) Smoking status (ever vs never smokers) ( 30643258) Youthful appearance (self-reported) ( 32339537)
Novel Interacting Genes		5 novel interacting genes: ALKBH2 POU4F1 RBM26 SLITRK6 SPRY2
Interacting Genes		9 interacting genes: AQP2 ITCH LYN NEDD4 NEDD4L SMURF1 UQCRH WWP2 YAP1
Entrez ID		54602
HPRD ID		17629
Ensembl ID		ENSG00000102471
Uniprot IDs		B4DGY6 Q9NV92
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Potassium Ion Export Across Plasma Membrane Potassium Channel Inhibitor Activity Regulation Of Potassium Ion Export Across Plasma Membrane Receptor Catabolic Process Negative Regulation Of Potassium Ion Transmembrane Transport Ubiquitin-protein Transferase Activity Negative Regulation Of Potassium Ion Transport Protein Polyubiquitination Transmembrane Transporter Binding Ubiquitin Protein Ligase Activity Receptor Metabolic Process Regulation Of Cell Projection Organization C-X-C Chemokine Receptor CXCR4 Signaling Pathway Protein Monoubiquitination Bud Elongation Involved In Lung Branching Regulation Of Nervous System Development Sodium Channel Inhibitor Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Developmental Process Positive Regulation Of Protein Metabolic Process Receptor Internalization Negative Regulation Of Cation Transmembrane Transport Protein K63-linked Ubiquitination Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Synapse Organization Regulation Of Monoatomic Cation Transmembrane Transport Branch Elongation Of An Epithelium Negative Regulation Of Signal Transduction Negative Regulation Of Sodium Ion Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Monoatomic Ion Transport Negative Regulation Of Signaling Negative Regulation Of Cell Communication Tolerance Induction Proline-rich Region Binding Protein Ubiquitination Axis Elongation Negative Regulation Of Transmembrane Transport Innervation Regulation Of Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Dendrite Extension Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Metal Ion Transport Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Regulation Of Neurogenesis Positive Regulation Of Macromolecule Metabolic Process
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