POU4F3

Description		POU class 4 homeobox 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Visual Perception Sensory Perception Of Sound Vestibulocochlear Nerve Development Cell Differentiation Retinal Ganglion Cell Axon Guidance Inner Ear Morphogenesis Inner Ear Auditory Receptor Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Axon Extension Inner Ear Development Neuromuscular Process Controlling Balance Neuron Apoptotic Process Inner Ear Receptor Cell Differentiation
Pathways
Drugs
Diseases		Deafness, autosomal dominant
GWAS		PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		7 interacting genes: AURKA DUSP21 GOLGA2 KRT31 KRTAP6-3 NHLRC4 PLA2G10
Entrez ID		5459
HPRD ID		03911
Ensembl ID		ENSG00000091010
Uniprot IDs		Q15319
PDB IDs
Enriched GO Terms of Interacting Partners?		Meiotic Spindle Assembly Meiotic Spindle Organization Negative Regulation Of Protein Binding Regulation Of Protein Binding Centrosome Cycle Mitotic Spindle Organization Organelle Disassembly Microtubule Organizing Center Organization Spindle Assembly Positive Regulation Of Reproductive Process Platelet Activating Factor Catabolic Process Reproductive Process Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Oocyte Maturation Lysophospholipid Transport Positive Regulation Of Protein Glycosylation Mitotic Spindle Spindle Pole Cytoskeleton Intermediate Filament Spindle Assembly Involved In Female Meiosis I Germinal Vesicle Histone H3S10 Kinase Activity Spindle Organization Golgi Disassembly Regulation Of Reproductive Process Chromosome Passenger Complex Mitotic Centrosome Separation Regulation Of Arachidonate Secretion Intestinal Stem Cell Homeostasis Positive Regulation Of Arachidonate Secretion Regulation Of Protein Glycosylation Pronucleus Axon Hillock 1-alkyl-2-acetylglycerophosphocholine Esterase Activity Positive Regulation Of Protein Metabolic Process Microtubule-based Process Positive Regulation Of Cell Maturation Platelet Activating Factor Metabolic Process Positive Regulation Of Acrosome Reaction Importin-alpha Family Protein Binding Golgi Ribbon Formation Golgi Cis Cisterna Membraneless Organelle Assembly Asymmetric Cell Division Cilium Disassembly Centrosome Separation Spindle Assembly Involved In Female Meiosis Calcium-dependent Phospholipase A2 Activity Phosphatidylcholine Catabolic Process
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