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DDIT4
Gene Name
DNA-damage-inducible transcript 4
Image
Gene Ontology Annotations
Cellular Component
Intracellular
Cytoplasm
Mitochondrion
Cytosol
Molecular Function
14-3-3 Protein Binding
Biological Process
Response To Hypoxia
Neuron Migration
Brain Development
Cell Proliferation
Negative Regulation Of Peptidyl-threonine Phosphorylation
Neuron Differentiation
Negative Regulation Of TOR Signaling
Negative Regulation Of Peptidyl-serine Phosphorylation
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Protein Complex Disassembly
Negative Regulation Of Glycolytic Process
Neurotrophin TRK Receptor Signaling Pathway
Defense Response To Virus
Reactive Oxygen Species Metabolic Process
Positive Regulation Of Neuron Death
Negative Regulation Of Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
5 interactors:
GSK3B
HSPA4
LRIF1
PDPK1
TXNIP
Entrez ID
54541
HPRD ID
09662
Ensembl ID
ENSG00000168209
Uniprot IDs
Q9NX09
PDB IDs
3LQ9
Enriched GO Terms of Interacting Partners
?
Protein Localization To Organelle
Extrinsic Apoptotic Signaling Pathway
Cellular Response To Tumor Cell
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cytoplasmic Transport
Phosphatidylinositol-mediated Signaling
Negative Regulation Of Catalytic Activity
Innate Immune Response
Negative Regulation Of Type B Pancreatic Cell Development
Superior Temporal Gyrus Development
Protein Import
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Intracellular Protein Transport
Re-entry Into Mitotic Cell Cycle
Negative Regulation Of Neuron Maturation
Response To Organic Substance
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Hypermethylation Of CpG Island
Protein Import Into Mitochondrial Outer Membrane
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Protein Kinase Activity
Response To Mechanical Stimulus
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Response To Abiotic Stimulus
Negative Regulation Of Kinase Activity
Cellular Response To Interleukin-3
Positive Regulation Of Intracellular Transport
Response To Tumor Cell
Nucleocytoplasmic Transport
Nuclear Transport
Fc Receptor Signaling Pathway
Regulation Of Neuron Maturation
Negative Regulation Of Glycogen (starch) Synthase Activity
Immune Response
Protein Localization To Microtubule
Negative Regulation Of Transferase Activity
Defense Response
Cellular Protein Localization
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Dendrite Morphogenesis
Negative Regulation Of Protein Phosphorylation
Response To Metal Ion
Negative Regulation Of NFAT Protein Import Into Nucleus
Protein Transport
Tagcloud
?
activates
anticancer
atf4
attenuated
autophagy
cebpb
chip
depletion
effectively
elusive
exo
genomic
greatly
largely
mitochondria
mtorc1
nude
pad
pan
perturbation
potentials
remain
resolution
responsive
sesn2
triple
unveiled
xenograft
yw3