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PLAUR
Gene Name
plasminogen activator, urokinase receptor
Image
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Focal Adhesion
Integral Component Of Membrane
Extrinsic Component Of Membrane
Anchored Component Of Membrane
Extracellular Vesicular Exosome
Invadopodium Membrane
Molecular Function
Receptor Activity
Receptor Binding
Protein Binding
Enzyme Binding
Protein Domain Specific Binding
Urokinase Plasminogen Activator Receptor Activity
Biological Process
C-terminal Protein Lipidation
Movement Of Cell Or Subcellular Component
Chemotaxis
Signal Transduction
Blood Coagulation
Attachment Of GPI Anchor To Protein
Regulation Of Proteolysis
Urokinase Plasminogen Activator Signaling Pathway
Fibrinolysis
Post-translational Protein Modification
Cellular Protein Metabolic Process
Pathways
Post-translational protein modification
Attachment of GPI anchor to uPAR
Dissolution of Fibrin Clot
Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Alteplase
Urokinase
Reteplase
Anistreplase
Tenecteplase
Diseases
GWAS
Protein-protein Interactions
20 interactors:
EEF1A1
ELAVL1
FAP
FYN
HCK
IGF2R
IL6ST
ITGAM
ITGB1
JAK1
KNG1
LRP1
LRP1B
MMP12
PFN2
PLAU
SRPX2
SURF2
TYK2
VTN
Entrez ID
5329
HPRD ID
01421
Ensembl ID
ENSG00000011422
Uniprot IDs
M0R1I2
Q03405
PDB IDs
1YWH
2FD6
2I9B
3BT1
3BT2
3U73
3U74
Enriched GO Terms of Interacting Partners
?
Cell Motility
Cell Migration
Locomotion
Peptidyl-tyrosine Autophosphorylation
Movement Of Cell Or Subcellular Component
Regulation Of Immune Response
Regulation Of Cell Proliferation
Regulation Of Collagen Catabolic Process
Peptidyl-tyrosine Phosphorylation
Regulation Of Immune System Process
Regulation Of Cell Migration
Regulation Of Smooth Muscle Cell Migration
Defense Response
Wound Healing
Regulation Of Cell Adhesion
Regulation Of Cell Motility
Developmental Process
Endocytosis
Regulation Of Apoptotic Process
Negative Regulation Of Blood Coagulation
Regulation Of Locomotion
Regulation Of Cellular Component Movement
Response To Wounding
Negative Regulation Of Coagulation
Regulation Of Cell Death
Blood Coagulation
Hemostasis
Protein Autophosphorylation
Negative Regulation Of Wound Healing
Cell Adhesion
Leukocyte Migration
Innate Immune Response
Regulation Of Innate Immune Response
Cell Adhesion Mediated By Integrin
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Cytokine-mediated Signaling Pathway
Regulation Of Blood Coagulation
Regulation Of Cellular Component Organization
Regulation Of Body Fluid Levels
Vesicle-mediated Transport
Activated T Cell Proliferation
Integrin-mediated Signaling Pathway
Regulation Of Wound Healing
Response To Stress
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Receptor-mediated Endocytosis
Regulation Of Cellular Process
Regulation Of Defense Response To Virus By Virus
Positive Regulation Of Cell Adhesion
Extracellular Matrix Organization
Tagcloud
?
alters
ap
attributed
cascade
chemo
chief
designating
erk1
fos
fra
govern
isoform
mapk
microrna
mir
mirna
multifaceted
next
oncogenic
serpine1
shortening
singular
snail
thousands
transcriptome
transcriptomes
tumorigenesis
utrs
zeb1