PGF

Gene Name		placental growth factor
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane
	Molecular Function	Protein Binding Growth Factor Activity Heparin Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Branching Involved In Ureteric Bud Morphogenesis Response To Hypoxia Positive Regulation Of Endothelial Cell Proliferation Sprouting Angiogenesis Signal Transduction Cell-cell Signaling Female Pregnancy Positive Regulation Of Cell Proliferation Cell Differentiation Organ Regeneration Cellular Response To Hormone Stimulus Response To Drug Positive Regulation Of Angiogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Division Regulation Of Morphogenesis Of A Branching Structure
Pathways		VEGF binds to VEGFR leading to receptor dimerization VEGF ligand-receptor interactions Signaling by VEGF
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: FLT1 NRP1 NRP2 VEGFA
Entrez ID		5228
HPRD ID		03076
Ensembl ID		ENSG00000119630
Uniprot IDs		G3XA84 P49763 Q53XY6 Q86TW6
PDB IDs		1FZV 1RV6
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Vestibulocochlear Nerve Structural Organization Positive Regulation Of Retinal Ganglion Cell Axon Guidance VEGF-activated Neuropilin Signaling Pathway Ganglion Morphogenesis Patterning Of Blood Vessels Angiogenesis Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Sprouting Angiogenesis Positive Regulation Of Cellular Component Movement Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Locomotion Sensory Neuron Axon Guidance Positive Regulation Of Endothelial Cell Proliferation Blood Vessel Morphogenesis Regulation Of Retinal Ganglion Cell Axon Guidance Positive Regulation Of Epithelial Cell Migration Pattern Specification Process Facioacoustic Ganglion Development Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Regulation Of Endothelial Cell Proliferation Blood Vessel Development Vasculature Development Coronary Artery Morphogenesis Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Ventral Trunk Neural Crest Cell Migration Regulation Of Endothelial Cell Migration Cellular Response To Growth Factor Stimulus Hypothalamus Cell Migration Neural Crest Cell Migration Involved In Autonomic Nervous System Development Trigeminal Ganglion Development Regulation Of Cell Migration Response To Growth Factor Chemotaxis Endothelial Cell Chemotaxis Positive Regulation Of Axon Extension Involved In Axon Guidance Semaphorin-plexin Signaling Pathway Involved In Neuron Projection Guidance Regulation Of Cell Motility Tissue Morphogenesis Hypothalamus Cell Differentiation Vestibulocochlear Nerve Development Axon Extension Involved In Axon Guidance Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Locomotion Regulation Of Cellular Component Movement Sympathetic Ganglion Development
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