PCSK2

Gene Name		proprotein convertase subtilisin/kexin type 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Membrane Transport Vesicle Dendrite Secretory Granule Lumen Perikaryon
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Protein Complex Binding
	Biological Process	Proteolysis Nervous System Development Protein Autoprocessing Insulin Processing Enkephalin Processing Islet Amyloid Polypeptide Processing Cellular Protein Metabolic Process
Pathways		Peptide hormone metabolism Insulin processing
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Dialysis-related mortality ( 21546767) Menarche (age at onset) ( 21102462) Obesity-related traits ( 23251661)
Protein-protein Interactions		3 interactors: IAPP PMCH SCG5
Entrez ID		5126
HPRD ID		01202
Ensembl ID		ENSG00000125851
Uniprot IDs		P16519
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuropeptide Signaling Pathway Feeding Behavior Negative Regulation Of Bone Resorption Negative Regulation Of Bone Remodeling Behavior Negative Regulation Of Tissue Remodeling Eating Behavior Regulation Of Bone Resorption Cell-cell Signaling Peptide Hormone Processing Regulation Of Bone Remodeling Endocrine Pancreas Development G-protein Coupled Receptor Signaling Pathway
Tagcloud ?		2kd abcc8 antigenic antigens atp2a2 autoantibodies candidates cd8 copyright destruction encoded glucagon goal infiltrating islet islets min6 nod pancreatic pathogenesis peg3 producing proglucagon protected recognize reserved rights scg2 specificities