GP6

Gene Name		glycoprotein VI (platelet)
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Extracellular Vesicular Exosome Tetraspanin-enriched Microdomain
	Molecular Function	Receptor Activity Transmembrane Signaling Receptor Activity Protein Binding Collagen Binding
	Biological Process	Enzyme Linked Receptor Protein Signaling Pathway Blood Coagulation Platelet Activation Leukocyte Migration
Pathways		Platelet Adhesion to exposed collagen GPVI-mediated activation cascade Platelet activation, signaling and aggregation Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Platelet aggregation ( 20526338)
Protein-protein Interactions		7 interactors: CRP FCER1G FCGR2A FCGR3A FYN LYN YES1
Entrez ID		51206
HPRD ID		10406
Ensembl ID		ENSG00000088053
Uniprot IDs		Q9HCN6
PDB IDs		2GI7
Enriched GO Terms of Interacting Partners?		Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Immune Response Endocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune System Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Immune Response Regulation Of Immune System Process Defense Response Vesicle-mediated Transport Innate Immune Response Immune System Process Peptidyl-tyrosine Autophosphorylation Wound Healing Leukocyte Migration Response To Wounding Positive Regulation Of Cell Activation T Cell Costimulation Response To Stress Ephrin Receptor Signaling Pathway Blood Coagulation Hemostasis Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Regulation Of Cell Activation Regulation Of Body Fluid Levels Chemotaxis Platelet Activation Transport Protein Autophosphorylation Positive Regulation Of T Cell Activation Regulation Of Mast Cell Degranulation Positive Regulation Of Neuron Projection Development Production Of Molecular Mediator Involved In Inflammatory Response Positive Regulation Of Homotypic Cell-cell Adhesion Fc-epsilon Receptor Signaling Pathway Regulation Of Platelet Activation Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Mast Cell Activation Regulation Of Mast Cell Activation Leukocyte Mediated Immunity Cell Migration Response To External Stimulus
Tagcloud ?		acetyl antiviral arrested assayed baculovirus classical csfv designated excluded fever flavivirus galactopyranosyl glucopyranosyl glycoproteins glycosylation insect investigating nitro pyridyl rns round sk6 steps sulfoxide swine tetra thio tri unrelated