PCK1

Gene Name		phosphoenolpyruvate carboxykinase 1 (soluble)
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Phosphoenolpyruvate Carboxykinase (GTP) Activity GTP Binding GDP Binding Manganese Ion Binding Carboxylic Acid Binding
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Oxaloacetate Metabolic Process Internal Protein Amino Acid Acetylation Pathogenesis Response To Activity Drug Metabolic Process Response To Insulin Glucose Homeostasis Small Molecule Metabolic Process Glycerol Biosynthetic Process From Pyruvate
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Transcriptional regulation of white adipocyte differentiation Glycogen storage diseases Metabolism of carbohydrates Abacavir transport and metabolism Abacavir metabolism
Drugs		Phosphoenolpyruvate 1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine 1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine Phosphomethylphosphonic Acid-Guanylate Ester
Diseases
GWAS		Response to fenofibrate (adiponectin levels) ( 23149075) Type 2 diabetes ( 23300278)
Protein-protein Interactions		4 interactors: APP C1R FBXO25 IKBKG
Entrez ID		5105
HPRD ID		02028
Ensembl ID		ENSG00000124253
Uniprot IDs		B4DT64 P35558
PDB IDs		1KHB 1KHE 1KHF 1KHG 1M51 1NHX 2GMV
Enriched GO Terms of Interacting Partners?		Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Innate Immune Response Synaptic Growth At Neuromuscular Junction Intracellular Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Immune Response Defense Response Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling
Tagcloud ?		3a adenovirus bidirectional c57bl cat complexities consequence exploration foxo foxo1 gluconeogenesis gluconeogenic hepatic hepatocytes ltcfdn mechanistic opposing opposite picture preferential pyruvate redundant repressive suppressing tcf tcf7l2 tcf7l2dn views wnt