BOLA1

Description		bolA family member 1
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GO Annotations	Cellular Component	Mitochondrion Iron-sulfur Cluster Assembly Complex
	Molecular Function	Protein Binding
	Biological Process	Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly Cell Redox Homeostasis
Pathways
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		9 interacting genes: APP BIRC2 BIRC7 C1orf94 GLRX5 HDX TXNRD3 XIAP ZNF572
Entrez ID		51027
HPRD ID		13036
Ensembl ID		ENSG00000178096
Uniprot IDs		Q9Y3E2
PDB IDs		5LCI
Enriched GO Terms of Interacting Partners?		Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Positive Regulation Of Post-translational Protein Modification Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Protein Polyubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of JNK Cascade Copper Ion Homeostasis Peptidase Inhibitor Activity Regulation Of JNK Cascade Protein Serine/threonine Kinase Binding Regulation Of Protein Polyubiquitination Regulation Of Protein Ubiquitination Cysteine-type Endopeptidase Inhibitor Activity Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Toll-like Receptor Signaling Pathway Cell Redox Homeostasis Regulation Of Post-translational Protein Modification Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Metabolic Process Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Canonical NF-kappaB Signal Transduction Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Natural Killer Cell Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Ubiquitin Protein Ligase Activity Apoptotic Process Cell Death Positive Regulation Of Protein Modification Process Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Regulation Of Inflammatory Response Response To CAMP Programmed Cell Death FBXO Family Protein Binding Positive Regulation Of Protein Linear Polyubiquitination Regulation Of Apoptosis Involved In Tissue Homeostasis Negative Regulation Of Cytokine-mediated Signaling Pathway Inorganic Ion Homeostasis Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Negative Regulation Of Response To Cytokine Stimulus Protein-folding Chaperone Binding Regulation Of Innate Immune Response Positive Regulation Of Protein K48-linked Ubiquitination Regulation Of Cell Cycle Regulation Of Non-canonical NF-kappaB Signal Transduction
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