PAX3

Gene Name		paired box 3
Image
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Neural Crest Cell Migration Neural Tube Closure Transcription From RNA Polymerase II Promoter Apoptotic Process Heart Development Muscle Organ Development Sensory Perception Of Sound Cell Proliferation Positive Regulation Of Cell Proliferation Organ Morphogenesis Regulation Of Somitogenesis Spinal Cord Association Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Developmental Pigmentation Neuron Fate Commitment Mammary Gland Specification
Pathways
Drugs
Diseases
GWAS		Facial morphology ( 22341974)
Protein-protein Interactions		15 interactors: CIB1 DAXX HDAC10 IPO13 MEOX1 MEOX2 MITF MSX1 POU3F2 RAD23B SOX10 SOX8 TAF1 TBP WWTR1
Entrez ID		5077
HPRD ID		09421
Ensembl ID		ENSG00000135903
Uniprot IDs		P23760
PDB IDs		3CMY
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Mesenchyme Development Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Stem Cell Differentiation Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Biosynthetic Process Mesenchymal Cell Differentiation Epithelium Development Tissue Development Glial Cell Differentiation Somite Specification Gliogenesis Regulation Of Cell Proliferation Oligodendrocyte Differentiation Organ Development Regulation Of Cell Differentiation Enteric Nervous System Development System Development Peripheral Nervous System Development Mesenchymal Cell Development
Tagcloud ?		6ped activators alveolar arms chimeric chromosomal copies cotransfected diphtheria effort exploit fkhr harbor lacks p36 pa3 pax7 plasmid plasmids prs q14 q35 rearrangements rhabdomyosarcoma sorting stably toxin transfections translocations