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SERPINB2
Description
serpin family B member 2
Image
GO Annotations
Cellular Component
Cornified Envelope
Extracellular Region
Extracellular Space
Cytoplasm
Plasma Membrane
Molecular Function
Serine-type Endopeptidase Inhibitor Activity
Peptidase Inhibitor Activity
Biological Process
Fibrinolysis
Negative Regulation Of Apoptotic Process
Pathways
Dissolution of Fibrin Clot
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Urokinase
Tenecteplase
Lanoteplase
Diseases
GWAS
Asthma (
31619474
)
Asthma (age of onset) (
31036433
)
Asthma (childhood onset) (
31036433
)
Hen's egg allergy (
29051540
)
Hip circumference adjusted for BMI (
28552196
)
Systolic blood pressure (
29208002
)
Novel Interacting Genes
1 novel interacting genes:
DCC
Interacting Genes
8 interacting genes:
APP
CDC42
IRF3
PLAU
PRPF8
PSMB1
RB1
UBE3A
Entrez ID
5055
HPRD ID
01420
Ensembl ID
ENSG00000197632
Uniprot IDs
P05120
PDB IDs
1BY7
1JRR
2ARQ
2ARR
Enriched GO Terms of Interacting Partners
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Acetylcholine Receptor Activator Activity
Amyloid-beta Complex
PTB Domain Binding
Apoptotic Process
Cell Projection Morphogenesis
Growth Cone Lamellipodium
Regulation Of Growth
Neuron Projection Organization
Positive Regulation Of Mitotic Cell Cycle
Collateral Sprouting In Absence Of Injury
Plasma Membrane Bounded Cell Projection Organization
Regulation Of Protein Import
Intracellular Signal Transduction
Response To Norepinephrine
Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Cellular Response To Oxygen-containing Compound
Modulation Of Chemical Synaptic Transmission
Regulation Of Response To Calcium Ion
Positive Regulation Of Cell Communication
Regulation Of Signal Transduction
Amylin Binding
Neuron Projection Morphogenesis
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Signaling
Regulation Of Proteolysis
Endosome To Plasma Membrane Transport Vesicle
Neuron Maturation
Programmed Cell Death
Negative Regulation Of Multicellular Organismal Process
Positive Regulation Of Toll Signaling Pathway
Positive Regulation Of Endothelin Production
Growth Cone Filopodium
Cellular Response To Norepinephrine Stimulus
Neuron Projection Development
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Receptor Ligand Activity
Endocytosis
Cell Surface Receptor Signaling Pathway
Regulation Of Inflammatory Response
Lipoprotein Particle
Cell Projection Organization
Positive Regulation Of Cell Cycle
Cell Death
Regulation Of Mitotic Cell Cycle
Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
Regulation Of Cell Communication
Positive Regulation Of Protein Import
Astrocyte Activation Involved In Immune Response
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