NT5E

Gene Name		5-nucleotidase, ecto (CD73)
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Surface Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding 5'-nucleotidase Activity Metal Ion Binding
	Biological Process	Purine Nucleobase Metabolic Process Purine Nucleotide Catabolic Process AMP Catabolic Process Pyrimidine Nucleobase Metabolic Process DNA Metabolic Process Dephosphorylation Small Molecule Metabolic Process Adenosine Biosynthetic Process Pyrimidine Nucleoside Catabolic Process Negative Regulation Of Inflammatory Response Nucleobase-containing Small Molecule Metabolic Process
Pathways		Purine catabolism Pyrimidine catabolism Purine metabolism Pyrimidine metabolism Metabolism of nucleotides
Drugs		Pentoxifylline
Diseases
GWAS		Metabolic traits ( 21886157)
Protein-protein Interactions		4 interactors: ACTB AFF1 FN1 LAMA1
Entrez ID		4907
HPRD ID		00552
Ensembl ID		ENSG00000135318
Uniprot IDs		P21589 Q6NZX3
PDB IDs		4H1S 4H1Y 4H2B 4H2F 4H2G 4H2I
Enriched GO Terms of Interacting Partners?		Cell Morphogenesis Involved In Differentiation Cell Morphogenesis Platelet Activation Cell Junction Assembly Cell Adhesion Locomotion Calcium-independent Cell-matrix Adhesion Retinal Blood Vessel Morphogenesis Establishment Of Epithelial Cell Apical/basal Polarity Movement Of Cell Or Subcellular Component Generation Of Neurons Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Neurogenesis Extracellular Matrix Organization Extracellular Structure Organization Axon Guidance Establishment Of Monopolar Cell Polarity Cell Development Blood Coagulation Blood Vessel Morphogenesis Hemostasis Integrin Activation Retina Vasculature Morphogenesis In Camera-type Eye Blood Vessel Development Axonogenesis Establishment Of Epithelial Cell Polarity Vasculature Development Axon Development Nervous System Development Regulation Of Body Fluid Levels Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Chemotaxis Retina Vasculature Development In Camera-type Eye Anatomical Structure Morphogenesis Morphogenesis Of A Polarized Epithelium Neuron Projection Morphogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity Cell Activation Response To Wounding Branching Involved In Salivary Gland Morphogenesis Substantia Nigra Development Endodermal Cell Differentiation Platelet Aggregation Acute-phase Response Neuron Projection Development Positive Regulation Of Axon Extension Cell Projection Morphogenesis
Tagcloud ?		amphiregulin areg betacellulin btc calgb cd73 cetuximab chemo dusp4 epgn epigen epiregulin erbb3 erbb4 ereg folfiri folfox formalin hbegf her3 her4 implicate kras mcrc modeled multiplicative pfs phlda1 tgfa