LSS

Gene Name		lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
Image
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Lipid Particle Membrane
	Molecular Function	Lanosterol Synthase Activity
	Biological Process	Cholesterol Biosynthetic Process Steroid Metabolic Process Small Molecule Metabolic Process
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) Cholesterol biosynthesis Metabolism of lipids and lipoproteins Activation of gene expression by SREBF (SREBP)
Drugs		R048-8071 Tetradecane Lanosterol
Diseases
GWAS
Protein-protein Interactions		1 interactors: NR4A1
Entrez ID		4047
HPRD ID		02945
Ensembl ID		ENSG00000160285
Uniprot IDs		B2R694 P48449
PDB IDs		1W6J 1W6K
Enriched GO Terms of Interacting Partners?		Endothelial Cell Chemotaxis Cell Migration Involved In Sprouting Angiogenesis Blood Vessel Endothelial Cell Migration Cellular Response To Vascular Endothelial Growth Factor Stimulus Sprouting Angiogenesis Skeletal Muscle Cell Differentiation Positive Regulation Of Endothelial Cell Proliferation Endothelial Cell Migration Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Endothelial Cell Proliferation Epithelial Cell Migration Epithelium Migration Steroid Hormone Mediated Signaling Pathway Skeletal Muscle Tissue Development Phosphatidylinositol-mediated Signaling Hormone-mediated Signaling Pathway Skeletal Muscle Organ Development Positive Regulation Of Epithelial Cell Proliferation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cell Chemotaxis Transcription Initiation From RNA Polymerase II Promoter Ameboidal-type Cell Migration Cellular Response To Steroid Hormone Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Intracellular Receptor Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway DNA-templated Transcription, Initiation Fc-epsilon Receptor Signaling Pathway
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