LSS

Name	lanosterol synthase
Structure
Novel Interactors	3 novel interactors: MX2 NUP214 SIRT5
Interactors	9 interactors: AQP6 CIB1 GPR35 NR4A1 SLC10A1 SLC10A6 TMEM167B TMEM86B YIF1A
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Membrane
	Molecular Function	Lanosterol Synthase Activity Protein Binding Isomerase Activity Intramolecular Transferase Activity
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Cholesterol Biosynthetic Process Triterpenoid Biosynthetic Process Regulation Of Protein Stability
Pathways	Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs	R048-8071 Lanosterol
GWAS	Glutathione peroxidase in non-alcoholic fatty liver disease x mastiha supplementation interaction ( 34025683 ) White blood cell count ( 27863252 )
Entrez ID	4047
HPRD ID	02945
Ensembl ID	ENSG00000160285
Uniprot IDs	B2R694 P48449
PDB IDs	1W6J 1W6K
GO Terms Enriched among Interactors ?	Bile Acid:sodium Symporter Activity Nitrate Transmembrane Transporter Activity Bile Acid And Bile Salt Transport Cytoplasmic Side Of Nuclear Pore Positive Regulation Of Male Germ Cell Proliferation Peptidyl-lysine Demalonylation Protein Demalonylation Protein Desuccinylation Peptidyl-lysine Desuccinylation Protein-malonyllysine Demalonylase Activity D-lysine 5,6-aminomutase Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Response To Ischemia PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Chemokine-mediated Signaling Pathway Protein-glutaryllysine Deglutarylase Activity Protein-succinyllysine Desuccinylase Activity Protein Deglutarylation Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Nuclear Pore Symporter Activity Endomitotic Cell Cycle Calcium-dependent Protein Kinase Inhibitor Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Import Into Nucleus Detection Of Lipopolysaccharide Cellular Response To Corticotropin-releasing Hormone Stimulus Protein Import Into Nucleus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane MRNA Transport Regulation Of Nucleocytoplasmic Transport Regulation Of Male Germ Cell Proliferation Histone Deacetylase Activity, NAD-dependent Monocarboxylic Acid Transport