KIR3DS1

Description		killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Protein Binding MHC Class I Receptor Activity
	Biological Process	Immune Response-regulating Signaling Pathway Immune Response Natural Killer Cell Activation
Pathways		DAP12 interactions
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: KIR3DL1 LAIR1
Interacting Genes		2 interacting genes: HLA-B TYROBP
Entrez ID		3813
HPRD ID		10034
Ensembl ID
Uniprot IDs		A0A0G2JN05 O43469 Q14943 Q4KN23 Q99565
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Immune Response Immune Response Natural Killer Cell Mediated Immunity Positive Regulation Of Leukocyte Mediated Cytotoxicity Regulation Of Immune System Process Positive Regulation Of Cell Killing Immune Response-regulating Signaling Pathway Immune System Process Innate Immune Response Secretory Granule Membrane Regulation Of Leukocyte Mediated Cytotoxicity Lymphocyte Mediated Immunity Defense Response To Other Organism Defense Response To Symbiont Regulation Of Interleukin-6 Production HLA-B Specific Inhibitory MHC Class I Receptor Activity Leukocyte Mediated Immunity Stimulatory Killer Cell Immunoglobulin-like Receptor Signaling Pathway TAP Binding Molecular Adaptor Activity Positive Regulation Of Osteoclast Development Positive Regulation Of Microglial Cell Mediated Cytotoxicity Positive Regulation Of Receptor Localization To Synapse Positive Regulation Of Macrophage Fusion Response To Other Organism Microglial Cell Activation Involved In Immune Response Positive Regulation Of Immune Effector Process Protection From Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Transforming Growth Factor Beta1 Production Defense Response Response To External Biotic Stimulus Adaptive Immune Response Regulation Of T Cell Anergy T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell MHC Class I Protein Complex Regulation Of Osteoclast Development Detection Of Bacterium Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Regulation Of T Cell Tolerance Induction Immune Effector Process Neutrophil Activation Involved In Immune Response Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Transforming Growth Factor Beta Production Signaling Receptor Binding Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Regulation Of Hemopoiesis Regulation Of Dendritic Cell Differentiation Regulation Of Innate Immune Response Negative Regulation Of B Cell Proliferation Regulation Of Tolerance Induction
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