KCNQ2

Gene Name		potassium channel, voltage gated KQT-like subfamily Q, member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Node Of Ranvier Axon Initial Segment
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Ankyrin Binding
	Biological Process	Potassium Ion Transport Synaptic Transmission Nervous System Development Axon Guidance Transmission Of Nerve Impulse Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Interaction between L1 and Ankyrins Axon guidance Potassium Channels L1CAM interactions Voltage gated Potassium channels
Drugs		Amitriptyline Diclofenac Meclofenamic acid Ezogabine
Diseases
GWAS
Protein-protein Interactions		6 interactors: ARIH2 CALM1 CALM2 CALM3 KCNQ3 PRKCA
Entrez ID		3785
HPRD ID		03757
Ensembl ID		ENSG00000075043
Uniprot IDs		O43526 Q4VXP7 Q53Y30
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Rhodopsin Mediated Signaling Pathway Activation Of Adenylate Cyclase Activity Rhodopsin Mediated Signaling Pathway Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Lyase Activity Regulation Of High Voltage-gated Calcium Channel Activity Activation Of Phospholipase C Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Adenylate Cyclase Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Phospholipase Activity Phototransduction, Visible Light Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of Phospholipase Activity Detection Of Calcium Ion Regulation Of CAMP Biosynthetic Process Positive Regulation Of Lipase Activity Detection Of Visible Light Regulation Of Cell Communication By Electrical Coupling Cellular Response To Light Stimulus Phototransduction Positive Regulation Of Phosphoprotein Phosphatase Activity Regulation Of CAMP Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Detection Of Light Stimulus Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Energy Reserve Metabolic Process Positive Regulation Of Monooxygenase Activity Cellular Response To Radiation Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Muscle Contraction Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Tagcloud ?		16p12 2q24 5q14 9q34 aetiology caln1 cdkl5 cgh cnv cnvs counselling ehmt1 encephalopathies encompassing epileptic etiological grin2a hypsarrhythmia infantile intronic iss magi2 mef2c microdeletions microduplications scn2a spasms stxbp1 xq28