KCNK1

Gene Name		potassium channel, two pore domain subfamily K, member 1
Image
Gene Ontology Annotations	Cellular Component	Endosome Plasma Membrane Voltage-gated Potassium Channel Complex Apical Plasma Membrane Brush Border Membrane
	Molecular Function	Inward Rectifier Potassium Channel Activity
	Biological Process	Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transmembrane Transport Response To Nicotine Potassium Ion Transmembrane Transport
Pathways		Tandem pore domain potassium channels Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) Potassium Channels
Drugs		Ibutilide Quinidine Quinidine barbiturate
Diseases
GWAS		Diabetic retinopathy ( 21441570) Periodontal microbiota ( 22699663)
Protein-protein Interactions		4 interactors: KRTAP10-3 SENP1 TCIRG1 UBE2I
Entrez ID		3775
HPRD ID		03447
Ensembl ID		ENSG00000135750
Uniprot IDs		O00180
PDB IDs		3UKM
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Positive Regulation Of SUMO Transferase Activity Post-translational Protein Modification Peptidyl-lysine Modification Protein Desumoylation Regulation Of Definitive Erythrocyte Differentiation Vacuolar Proton-transporting V-type ATPase Complex Assembly Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Vacuolar Acidification Protein Modification By Small Protein Conjugation Intracellular PH Reduction PH Reduction
Tagcloud ?		actinomycetemcomitans affymetrix aggregatibacter camta1 ceu characterizes checkerboard colonization correction direction fbxo38 genotyping gwa hapmap il33 imputation loci microbiome microbiota orange periodontal periodontitis replicating runx2 shifts suggestive trps1 uhrf2 vamp3