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KCNJ11
Gene Name
potassium channel, inwardly rectifying subfamily J, member 11
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Envelope
Mitochondrion
Endosome
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Voltage-gated Potassium Channel Complex
ATP-sensitive Potassium Channel Complex
Intercalated Disc
T-tubule
Axolemma
Neuronal Cell Body
Myelin Sheath
Cell Body Fiber
Molecular Function
Voltage-gated Potassium Channel Activity
ATP Binding
Protein C-terminus Binding
ATP-activated Inward Rectifier Potassium Channel Activity
G-protein Activated Inward Rectifier Potassium Channel Activity
Ankyrin Binding
Potassium Ion Binding
Heat Shock Protein Binding
Ion Channel Binding
Biological Process
Response To Ischemia
Glucose Metabolic Process
Energy Reserve Metabolic Process
Synaptic Transmission
Potassium Ion Import
Response To Estradiol
Response To ATP
Response To Testosterone
Regulation Of Ion Transmembrane Transport
Regulation Of Membrane Potential
Response To Drug
Small Molecule Metabolic Process
Negative Regulation Of Insulin Secretion
Regulation Of Insulin Secretion
Neurological System Process
Cellular Response To Nicotine
Cellular Response To Glucose Stimulus
Cellular Response To Tumor Necrosis Factor
Potassium Ion Transmembrane Transport
Positive Regulation Of Cation Channel Activity
Pathways
Inwardly rectifying K+ channels
Integration of energy metabolism
ATP sensitive Potassium channels
Regulation of insulin secretion
Potassium Channels
Drugs
Glimepiride
Ibutilide
Verapamil
Levosimendan
Glyburide
Diazoxide
Thiamylal
Diseases
GWAS
Type 2 diabetes (
18372903
17463246
17463248
17463249
19056611
)
Protein-protein Interactions
6 interactors:
ABCC8
ABCC9
AP2M1
KCNJ2
KCNJ8
LDHA
Entrez ID
3767
HPRD ID
09022
Ensembl ID
ENSG00000187486
Uniprot IDs
B2RC52
Q14654
PDB IDs
Enriched GO Terms of Interacting Partners
?
Potassium Ion Import
Potassium Ion Transmembrane Transport
Synaptic Transmission
Potassium Ion Transport
Cell-cell Signaling
Monovalent Inorganic Cation Transport
Response To External Stimulus
Metal Ion Transport
Cation Transmembrane Transport
Cation Transport
Ion Transmembrane Transport
Cell Communication
Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential
Transmembrane Transport
Ion Transport
Relaxation Of Skeletal Muscle
Defense Response To Virus
Response To Stimulus
Response To Virus
Regulation Of Resting Membrane Potential
Transport
Cellular Potassium Ion Homeostasis
Regulation Of Skeletal Muscle Contraction
Membrane Repolarization During Cardiac Muscle Cell Action Potential
Membrane Repolarization During Action Potential
Membrane Depolarization During Cardiac Muscle Cell Action Potential
Membrane Repolarization
Relaxation Of Cardiac Muscle
Potassium Ion Homeostasis
Signaling
Generation Of Precursor Metabolites And Energy
Positive Regulation Of Potassium Ion Transmembrane Transport
Regulation Of Ion Transmembrane Transport
Negative Regulation Of Protein Localization To Plasma Membrane
Relaxation Of Muscle
Regulation Of Membrane Repolarization
Regulation Of Heart Rate By Cardiac Conduction
Magnesium Ion Transport
Regulation Of Defense Response To Virus By Virus
Cardiac Muscle Cell Action Potential Involved In Contraction
Positive Regulation Of Potassium Ion Transport
Cellular Response To Stimulus
Vasodilation
Membrane Depolarization During Action Potential
Response To PH
Cardiac Muscle Cell Action Potential
Clathrin-mediated Endocytosis
Substantia Nigra Development
Regulation Of Ion Transport
Regulation Of Potassium Ion Transmembrane Transport
Tagcloud
?
5x10
asian
cdkal1
cdkn2a
cgs
discriminative
gwas
hhex
hnf1b
homa
igf2bp2
jazf1
kcnq1
marginally
modestly
nominal
notch2
nri
reclassification
relating
replicated
roc
slc30a8
summing
t2d
tcf7l2
unweighted
weighted
wfs1