CYR61

Gene Name		cysteine-rich, angiogenic inducer, 61
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Matrix
	Molecular Function	Integrin Binding Insulin-like Growth Factor Binding Heparin Binding Extracellular Matrix Binding
	Biological Process	Regulation Of Cell Growth Osteoblast Differentiation Positive Regulation Of Protein Phosphorylation Intussusceptive Angiogenesis Atrioventricular Valve Morphogenesis Apoptotic Process Involved In Heart Morphogenesis Ventricular Septum Development Chemotaxis Cell Adhesion Cell-cell Signaling Cell Proliferation Anatomical Structure Morphogenesis Positive Regulation Of Phospholipase Activity Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Positive Regulation Of Cell Migration Positive Regulation Of BMP Signaling Pathway Positive Regulation Of Osteoblast Proliferation Negative Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Wound Healing, Spreading Of Cells Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Atrial Septum Morphogenesis Negative Regulation Of Cell Death Chondroblast Differentiation Chorio-allantoic Fusion Labyrinthine Layer Blood Vessel Development Positive Regulation Of Cartilage Development Regulation Of ERK1 And ERK2 Cascade Reactive Oxygen Species Metabolic Process Positive Regulation Of Ceramide Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: ITGAV ITGB5
Entrez ID		3491
HPRD ID		09089
Ensembl ID		ENSG00000142871
Uniprot IDs		O00622 Q6FI18
PDB IDs
Enriched GO Terms of Interacting Partners?		Endodermal Cell Differentiation Endoderm Formation Endoderm Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Integrin-mediated Signaling Pathway Formation Of Primary Germ Layer Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Cell-matrix Adhesion Gastrulation Negative Regulation Of Entry Of Bacterium Into Host Cell Entry Of Symbiont Into Host Cell By Promotion Of Host Phagocytosis Cell-substrate Adhesion Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Regulation Of Entry Of Bacterium Into Host Cell Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization Negative Regulation Of Receptor Biosynthetic Process Apolipoprotein A-I-mediated Signaling Pathway Single Organismal Cell-cell Adhesion Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Lipoprotein Metabolic Process Embryonic Morphogenesis Positive Regulation Of Osteoblast Proliferation Regulation Of Apoptotic Cell Clearance Regulation Of Lipoprotein Metabolic Process Stress Fiber Assembly Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Receptor Biosynthetic Process ERK1 And ERK2 Cascade Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Lipid Storage Negative Chemotaxis Heterotypic Cell-cell Adhesion Negative Regulation Of Lipid Transport Regulation Of Osteoblast Proliferation Anatomical Structure Formation Involved In Morphogenesis Embryo Development Cell Adhesion Apoptotic Cell Clearance Epithelial Cell-cell Adhesion Viral Entry Into Host Cell Entry Into Host Cell Substrate Adhesion-dependent Cell Spreading Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Phagocytosis Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Lipid Storage
Tagcloud ?		axis belongs canonical catenin ccn ccn6 closely collagen collagens ctgf cysteine cytoplasm dysregulated fibronectin gastric indicates inducible invasion matricellular nov positively silencing suppressed tcf transferring validation wisp3 wnt wnt1