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IFNG
Gene Name
interferon, gamma
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
External Side Of Plasma Membrane
Molecular Function
Cytokine Activity
Interferon-gamma Receptor Binding
Biological Process
Protein Import Into Nucleus, Translocation
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Neutrophil Apoptotic Process
Regulation Of The Force Of Heart Contraction
Positive Regulation Of Mesenchymal Cell Proliferation
Adaptive Immune Response
CD8-positive, Alpha-beta T Cell Differentiation Involved In Immune Response
Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Apoptotic Process
Movement Of Cell Or Subcellular Component
Humoral Immune Response
Cell Cycle Arrest
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Proliferation
Response To Virus
Cytokine-mediated Signaling Pathway
Antigen Processing And Presentation
Neutrophil Chemotaxis
Negative Regulation Of Epithelial Cell Differentiation
Endoplasmic Reticulum Unfolded Protein Response
Negative Regulation Of Myelination
Positive Regulation Of Synaptic Transmission, Cholinergic
Negative Regulation Of Interleukin-17 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-23 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein
Positive Regulation Of Smooth Muscle Cell Apoptotic Process
Positive Regulation Of T Cell Proliferation
Response To Drug
Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein
Defense Response To Bacterium
Defense Response To Protozoan
Negative Regulation Of Growth Of Symbiont In Host
Positive Regulation Of Chemokine Biosynthetic Process
Positive Regulation Of Interleukin-12 Biosynthetic Process
Positive Regulation Of MHC Class II Biosynthetic Process
Positive Regulation Of Interleukin-6 Biosynthetic Process
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Osteoclast Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Isotype Switching To IgG Isotypes
Negative Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Interleukin-1 Beta Secretion
Regulation Of Insulin Secretion
Sensory Perception Of Mechanical Stimulus
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Defense Response To Virus
Positive Regulation Of Killing Of Cells Of Other Organism
Interferon-gamma-mediated Signaling Pathway
Regulation Of Interferon-gamma-mediated Signaling Pathway
Positive Regulation Of Fructose 1,6-bisphosphate 1-phosphatase Activity
Positive Regulation Of Fructose 1,6-bisphosphate Metabolic Process
Positive Regulation Of Vitamin D Biosynthetic Process
Positive Regulation Of Calcidiol 1-monooxygenase Activity
Cellular Response To Lipopolysaccharide
Cellular Response To Interleukin-18
Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
Extrinsic Apoptotic Signaling Pathway
Regulation Of Neuronal Action Potential
Positive Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production
Regulation Of Hepatocyte Proliferation
Pathways
Interferon gamma signaling
Interferon Signaling
Cytokine Signaling in Immune system
Regulation of IFNG signaling
Drugs
Olsalazine
Glucosamine
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Ulcerative colitis (
20228799
21297633
19122664
)
Protein-protein Interactions
5 interactors:
IFNGR1
IFNGR2
PDIA3
STAT6
TNF
Entrez ID
3458
HPRD ID
00957
Ensembl ID
ENSG00000111537
Uniprot IDs
P01579
PDB IDs
1EKU
1FG9
1FYH
1HIG
3BES
Enriched GO Terms of Interacting Partners
?
Cytokine-mediated Signaling Pathway
Cellular Response To Cytokine Stimulus
Response To Cytokine
Immune System Process
Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Response To Interferon-gamma
Regulation Of Immune Response
Response To Virus
Positive Regulation Of Immunoglobulin Mediated Immune Response
Immune Response
Regulation Of Immune System Process
Defense Response
Response To Stress
Epithelial Cell Proliferation
Regulation Of Cytokine-mediated Signaling Pathway
Cellular Response To Organic Substance
Negative Regulation Of Branching Involved In Lung Morphogenesis
Negative Regulation Of L-glutamate Transport
Protein Import Into Nucleus
Negative Regulation Of Immune Response
Response To Other Organism
Nuclear Import
Interferon-gamma-mediated Signaling Pathway
Response To Biotic Stimulus
Positive Regulation Of Adaptive Immune Response
Innate Immune Response
Cellular Response To Interferon-gamma
T-helper 1 Cell Lineage Commitment
Positive Regulation Of Translational Initiation By Iron
Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus
Response To Gold Nanoparticle
Gland Morphogenesis
Protein Import
Response To Interferon-gamma
Protein Localization To Nucleus
Signal Transduction
Response To Organic Substance
Positive Regulation Of Interleukin-18 Production
Chronic Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Calcidiol 1-monooxygenase Activity
Positive Regulation Of Vitamin D Biosynthetic Process
Positive Regulation Of Mononuclear Cell Migration
Sequestering Of Triglyceride
Regulation Of Adaptive Immune Response
Regulation Of Extrinsic Apoptotic Signaling Pathway
Signaling
Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Interleukin-4-mediated Signaling Pathway
Positive Regulation Of Isotype Switching To IgE Isotypes
Cell Communication
Tagcloud
?
30min
ancestry
asks
asleep
habitual
ifngr1
il10
il13
il17a
il1b
il1r2
il2
il4
il6
il8
interleukins
nfkb1
nfkb2
pittsburgh
rs1143623
rs1143642
rs1295686
rs2857602
rs4648110
rs4719714
soi
strengthens
tnfa
transgender