ACADM

Gene Name		acyl-CoA dehydrogenase, C-4 to C-12 straight chain
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Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Axon Extracellular Vesicular Exosome
	Molecular Function	Acyl-CoA Dehydrogenase Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding Medium-chain-acyl-CoA Dehydrogenase Activity
	Biological Process	Fatty Acid Beta-oxidation Carnitine Metabolic Process, CoA-linked Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Cellular Lipid Metabolic Process Small Molecule Metabolic Process Carnitine Biosynthetic Process Medium-chain Fatty Acid Metabolic Process Medium-chain Fatty Acid Catabolic Process Oxidation-reduction Process
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Beta oxidation of octanoyl-CoA to hexanoyl-CoA mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Mitochondrial Fatty Acid Beta-Oxidation mitochondrial fatty acid beta-oxidation of saturated fatty acids Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs		Octanoyl-Coenzyme A Flavin-Adenine Dinucleotide 3-Thiaoctanoyl-Coenzyme A
Diseases
GWAS		Metabolic traits ( 21886157) Metabolite levels ( 20037589)
Protein-protein Interactions		2 interactors: CALM1 SUMO4
Entrez ID		34
HPRD ID		08447
Ensembl ID		ENSG00000117054
Uniprot IDs		B4DVB1 B7Z9I1 P11310
PDB IDs		1EGC 1EGD 1EGE 1T9G 2A1T
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Protein Sumoylation Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine Positive Regulation Of Adenylate Cyclase Activity Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Nitric-oxide Synthase Activity Response To Mineralocorticoid Substantia Nigra Development Positive Regulation Of Oxidoreductase Activity Negative Regulation Of Transporter Activity Negative Regulation Of Calcium Ion Transport Positive Regulation Of Lyase Activity Positive Regulation Of Dephosphorylation Negative Regulation Of Ion Transmembrane Transport Response To Amine Inositol Phosphate Metabolic Process Activation Of Phospholipase C Activity See more
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