AGFG1

Description		ArfGAP with FG repeats 1
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GO Annotations	Cellular Component	Nucleus Nuclear Pore Cytoplasm Cytosol Cytoplasmic Vesicle Cell Projection Neuronal Cell Body
	Molecular Function	DNA Binding RNA Binding GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Acrosome Assembly MRNA Export From Nucleus Spermatogenesis Spermatid Nucleus Differentiation Cell Differentiation Intermediate Filament Organization MRNA Transport
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Airway hyperresponsiveness ( 23984888) Asthma ( 31959851) Mild influenza (H1N1) infection ( 26379185)
Novel Interacting Genes		1 novel interacting genes: CUL3
Interacting Genes		15 interacting genes: APC APP DNAJC5 EPS15 EPS15L1 ITSN1 MFHAS1 NYAP2 OGT PKIA POLE2 RNF216 TRIM54 VAMP7 XPO1
Entrez ID		3267
HPRD ID		02918
Ensembl ID		ENSG00000173744
Uniprot IDs		A0A0S2Z444 P52594
PDB IDs		2D9L 2OLM 2VX8
Enriched GO Terms of Interacting Partners?		Clathrin-coated Pit Vesicle-mediated Transport In Synapse Regulation Of Protein Localization Negative Regulation Of Protein Localization To Nucleus Clathrin Coat Of Coated Pit Establishment Of Localization In Cell Postsynaptic Endocytic Zone Vesicle-mediated Transport Intracellular Transport Platelet Alpha Granule Cytoplasm Plasma Membrane Bounded Cell Projection Cellular Localization Regulation Of Protein Catabolic Process Negative Regulation Of Microtubule Depolymerization Regulation Of Protein Localization To Nucleus Regulation Of Microtubule Depolymerization Negative Regulation Of Protein Serine/threonine Kinase Activity Intracellular Signal Transduction Negative Regulation Of Microtubule Polymerization Or Depolymerization Lamellipodium Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Signaling Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Endocytosis Cytoplasmic Vesicle Negative Regulation Of CAMP-dependent Protein Kinase Activity Presynaptic Endocytosis Synaptic Vesicle Endocytosis Exocytosis Negative Regulation Of Type I Interferon Production Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Signal Transduction Regulation Of Mitotic Cell Cycle Protein-containing Complex Organization Apoptotic Process Presynapse Regulation Of Glycolytic Process Programmed Cell Death Negative Regulation Of Protein Localization Synapse Protein-macromolecule Adaptor Activity Azurophil Granule Membrane Cell Death
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