HMGB3

Name	high mobility group box 3
Structure
Interactors	9 interactors: CEBPA HMGA1 MEOX1 MEOX2 PAX5 PAX6 RPRD1B SDCBP TERF2IP
GO Annotations	Cellular Component	Nucleus Chromosome Cytoplasm
	Molecular Function	Four-way Junction DNA Binding DNA Binding Double-stranded DNA Binding RNA Binding Protein Binding DNA Binding, Bending
	Biological Process	Immune System Process DNA Recombination DNA Geometric Change Innate Immune Response Negative Regulation Of B Cell Differentiation Negative Regulation Of Myeloid Cell Differentiation
GWAS	No GWAS studies recorded
Entrez ID	3149
HPRD ID	02181
Ensembl ID	ENSG00000029993
Uniprot IDs	O15347
PDB IDs	2EQZ 2YQI
GO Terms Enriched among Interactors ?	HMG Box Domain Binding Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Somite Specification Chromatin Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Segment Specification Somite Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Sequence-specific DNA Binding Chromatin Binding Regulation Of Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nucleus Nucleic Acid Metabolic Process DNA Binding Transcription Coregulator Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Embryonic Pattern Specification RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Interleukin-5 Receptor Complex Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Cell Population Proliferation Nucleoplasm Cerebral Cortex Development