HK2

Gene Name		hexokinase 2
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Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Cytosol Membrane
	Molecular Function	Glucokinase Activity Hexokinase Activity ATP Binding Glucose Binding Fructokinase Activity Mannokinase Activity
	Biological Process	Cellular Glucose Homeostasis Response To Ischemia Carbohydrate Metabolic Process Glucose Metabolic Process Glycolytic Process Lactation Apoptotic Mitochondrial Changes Hexose Transport Pathogenesis Glucose Transport Small Molecule Metabolic Process Regulation Of Glucose Import Carbohydrate Phosphorylation Glucose 6-phosphate Metabolic Process Transmembrane Transport
Pathways		Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates Glucose transport SLC-mediated transmembrane transport Hexose transport
Drugs
Diseases
GWAS		Femoral neck bone geometry ( 22087292)
Protein-protein Interactions		7 interactors: MAGEA12 PRKCE PTGDS SLC2A4 UBQLN1 UBQLN4 ZBTB17
Entrez ID		3099
HPRD ID		03080
Ensembl ID		ENSG00000159399
Uniprot IDs		P52789
PDB IDs		2NZT
Enriched GO Terms of Interacting Partners?		Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Response To Hypoxia Positive Regulation Of Cellular Glucuronidation Amylopectin Biosynthetic Process Cellular Response To Stress TRAM-dependent Toll-like Receptor 4 Signaling Pathway Response To Ethanol Response To Endoplasmic Reticulum Stress Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Protein Metabolic Process Cellular Response To Ethanol Glucose Import Response To Abiotic Stimulus Positive Regulation Of Fibroblast Migration Macrophage Activation Involved In Immune Response Locomotory Exploration Behavior Response To Organic Substance Negative Regulation Of Sodium Ion Transport
Tagcloud ?		acly anabolism bioenergetic bioenergetics chemoresistance clarified clearer complexified concepts dialog dysfunctional facets flexibility glutamine ldha likewise microenvironmental modulators mycn oncometabolites owing pgam1 progressed proof remodel stroma symbiosis translated warburg