SOCS7

Gene Name		suppressor of cytokine signaling 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Kinase Inhibitor Activity Protein Binding SH3 Domain Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Biological_process Insulin Receptor Signaling Pathway Protein Ubiquitination Cytokine-mediated Signaling Pathway Intracellular Signal Transduction Regulation Of Growth Fat Cell Differentiation Negative Regulation Of JAK-STAT Cascade
Pathways
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)
Protein-protein Interactions		11 interactors: EGFR GRB2 IRS2 IRS4 NCK1 PIK3R1 PIK3R2 PLCG1 SORBS3 TUBA1A TUBB4B
Entrez ID		30837
HPRD ID		12299
Ensembl ID
Uniprot IDs		J9JID8 O14512
PDB IDs
Enriched GO Terms of Interacting Partners?		Fc Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Phosphatidylinositol-mediated Signaling Insulin Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Immune Response Regulation Of Phosphorylation Defense Response Cellular Response To Insulin Stimulus Cellular Response To Organonitrogen Compound Regulation Of Immune Response Regulation Of Phosphorus Metabolic Process Phagocytosis Cellular Response To Growth Factor Stimulus Cellular Response To Hormone Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Growth Factor Response To Insulin T Cell Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Organic Substance Positive Regulation Of Signal Transduction Antigen Receptor-mediated Signaling Pathway Regulation Of Immune System Process Regulation Of Signaling Regulation Of Kinase Activity Immune System Process Response To Organonitrogen Compound Cell Migration Movement Of Cell Or Subcellular Component Response To Peptide Hormone Positive Regulation Of Immune System Process Cell Motility Response To Peptide
Tagcloud ?		accumulates adapter atr becoming cleavage coordination cytoskeletal depleted depletion discrete hela hyperactive increasingly interconnectedness interconnectivity irradiation monitored mostly nck nck1 nck2 parp phenocopies redundant shortly strikingly translocation undergo uv