HBD

Description		hemoglobin subunit delta
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GO Annotations	Cellular Component	Cytosol Hemoglobin Complex Haptoglobin-hemoglobin Complex Blood Microparticle
	Molecular Function	Oxygen Carrier Activity Protein Binding Oxygen Binding Heme Binding Hemoglobin Alpha Binding Metal Ion Binding
	Biological Process	Carbon Dioxide Transport Oxygen Transport Erythrocyte Development
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Beta thalassemia/hemoglobin E disease ( 20183929) Hematology traits ( 23263863) Hemoglobin levels ( 26366553) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Malaria ( 31844061) Mean corpuscular hemoglobin concentration ( 23263863)
Interacting Genes		6 interacting genes: APP HBA1 HBA2 HBM HBQ1 HBZ
Entrez ID		3045
HPRD ID		00787
Ensembl ID		ENSG00000223609
Uniprot IDs		A0N071 P02042
PDB IDs		1SHR 1SI4
Enriched GO Terms of Interacting Partners?		Hemoglobin Complex Haptoglobin-hemoglobin Complex Oxygen Carrier Activity Myeloid Cell Development Oxygen Transport Oxygen Binding Erythrocyte Development Hemopoiesis Heme Binding Carbon Dioxide Transport Cell Development Iron Ion Binding One-carbon Compound Transport Haptoglobin Binding Nitric Oxide Transport G Protein-coupled Receptor Binding Endocytic Vesicle Lumen Hydrogen Peroxide Catabolic Process Cellular Developmental Process Peroxidase Activity Hydrogen Peroxide Metabolic Process Metal Ion Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Oxidant Detoxification Reactive Oxygen Species Metabolic Process Response To Hydrogen Peroxide Cellular Detoxification Acetylcholine Receptor Activator Activity Lipoprotein Particle Developmental Process Positive Regulation Of Protein Import Blood Microparticle PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cell Maturation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response
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