GPX4

Gene Name		glutathione peroxidase 4
Image
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Extracellular Vesicular Exosome
	Molecular Function	Glutathione Peroxidase Activity Selenium Binding Glutathione Binding Phospholipid-hydroperoxide Glutathione Peroxidase Activity
	Biological Process	Phospholipid Metabolic Process Glutathione Metabolic Process Response To Oxidative Stress Multicellular Organismal Development Aging Arachidonic Acid Metabolic Process Lipoxygenase Pathway Response To Estradiol Hydrogen Peroxide Catabolic Process Small Molecule Metabolic Process Regulation Of Inflammatory Response Oxidation-reduction Process
Pathways		Arachidonic acid metabolism Synthesis of 5-eicosatetraenoic acids Metabolism of lipids and lipoproteins Synthesis of 12-eicosatetraenoic acid derivatives Synthesis of 15-eicosatetraenoic acid derivatives
Drugs		Glutathione
Diseases
GWAS		Crohn's disease ( 21102463 23128233)
Protein-protein Interactions		2 interactors: MAPK13 PRDX6
Entrez ID		2879
HPRD ID		11819
Ensembl ID		ENSG00000167468
Uniprot IDs		P36969
PDB IDs		2GS3 2OBI
Enriched GO Terms of Interacting Partners?
Tagcloud ?		biopsies chc cohorts drive eliminates elimination eradication fusogenic glutathione hcv hepatocarcinogenesis hepatocellular infectivity lipoproteins liposome modulating ns5a peroxidase peroxide peroxides phosphatidylinositol regimens replicative returned ros scavenger scavengers tightly virions