XCR1

Gene Name		chemokine (C motif) receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Chemokine Receptor Activity
	Biological Process	Chemotaxis Inflammatory Response G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Release Of Sequestered Calcium Ion Into Cytosol Chemokine-mediated Signaling Pathway
Pathways		G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: XCL1 XCL2
Entrez ID		2829
HPRD ID		02774
Ensembl ID		ENSG00000173578
Uniprot IDs		P46094 Q502V0 Q689E2
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Positive Regulation Of Granzyme A Production Negative Regulation Of T-helper 1 Cell Activation Positive Regulation Of CD8-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Immunoglobulin Production In Mucosal Tissue Positive Regulation Of T-helper 1 Cell Cytokine Production Mature Natural Killer Cell Chemotaxis Positive Regulation Of Granzyme B Production Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Thymocyte Migration Natural Killer Cell Chemotaxis Regulation Of CD8-positive, Alpha-beta T Cell Proliferation Negative Regulation Of T Cell Cytokine Production Positive Regulation Of Natural Killer Cell Chemotaxis Positive Regulation Of B Cell Chemotaxis Chemotaxis Negative Regulation Of T-helper 1 Type Immune Response Negative Regulation Of Alpha-beta T Cell Proliferation Positive Regulation Of T Cell Chemotaxis Positive Regulation Of T-helper 2 Cell Cytokine Production Positive Regulation Of T-helper 1 Type Immune Response Negative Regulation Of T Cell Mediated Immunity Positive Regulation Of Alpha-beta T Cell Proliferation Cell Migration Lymphocyte Chemotaxis Cell Motility Positive Regulation Of T Cell Cytokine Production Positive Regulation Of T Cell Migration Negative Regulation Of Interleukin-2 Production Regulation Of T Cell Migration Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Neutrophil Chemotaxis Negative Regulation Of Alpha-beta T Cell Activation Regulation Of T Cell Cytokine Production Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Type 2 Immune Response Regulation Of Neutrophil Chemotaxis Lymphocyte Migration Positive Regulation Of Interleukin-10 Production Regulation Of Neutrophil Migration Regulation Of Lymphocyte Migration Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Locomotion Positive Regulation Of Immunoglobulin Mediated Immune Response Negative Regulation Of Interferon-gamma Production Release Of Sequestered Calcium Ion Into Cytosol Immune Response Regulation Of Granulocyte Chemotaxis
Tagcloud ?		12p70 9a abs adjuvants cadm1 cd141 cd1c counterparts dc dec dissect flt3 humanized incorporating lambda lectin lesser pdc phenotypically plasmacytoid polycytidylic polyinosinic producers reconstitution spleen subsets tlr3 tlr4 tlr9