C5AR2

Gene Name		complement component 5a receptor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Basal Plasma Membrane Integral Component Of Membrane Apical Part Of Cell
	Molecular Function	C5a Anaphylatoxin Receptor Activity Protein Binding
	Biological Process	Chemotaxis Inflammatory Response G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neutrophil Chemotaxis Negative Regulation Of Interleukin-6 Secretion Regulation Of Interleukin-8 Secretion
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: C3 C4A C5AR1
Entrez ID		27202
HPRD ID		17072
Ensembl ID		ENSG00000134830
Uniprot IDs		Q9P296
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Apoptotic Cell Clearance Regulation Of Apoptotic Cell Clearance Regulation Of Complement Activation Inflammatory Response Positive Regulation Of Phagocytosis Regulation Of Humoral Immune Response Positive Regulation Of Immune Response Regulation Of Phagocytosis Regulation Of Acute Inflammatory Response Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Endocytosis Complement Activation, Classical Pathway Humoral Immune Response Mediated By Circulating Immunoglobulin Complement Activation Complement Component C5a Signaling Pathway Protein Activation Cascade Immune Response Immunoglobulin Mediated Immune Response Regulation Of Immune System Process B Cell Mediated Immunity Regulation Of Endocytosis Defense Response Positive Regulation Of Type IIa Hypersensitivity Humoral Immune Response Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Negative Regulation Of Endopeptidase Activity Leukocyte Mediated Immunity Adaptive Immune Response Negative Regulation Of Peptidase Activity Regulation Of Inflammatory Response Positive Regulation Of Activation Of Membrane Attack Complex Cell Proliferation In Hindbrain Complement Receptor Mediated Signaling Pathway Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Vesicle-mediated Transport Immune System Process Regulation Of Endopeptidase Activity Positive Regulation Of Hypersensitivity Regulation Of Protein Metabolic Process Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Catalytic Activity Complement Activation, Alternative Pathway Positive Regulation Of Inflammatory Response To Antigenic Stimulus MRNA Transcription From RNA Polymerase II Promoter
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