GHSR

Gene Name		growth hormone secretagogue receptor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Neuron Projection Membrane Raft
	Molecular Function	Growth Hormone Secretagogue Receptor Activity G-protein Coupled Receptor Activity Growth Hormone-releasing Hormone Receptor Activity Peptide Hormone Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway Actin Polymerization Or Depolymerization Adult Feeding Behavior Response To Hormone Hormone-mediated Signaling Pathway Growth Hormone Secretion Response To Food Positive Regulation Of Appetite Negative Regulation Of Interleukin-1 Beta Production Cellular Response To Insulin Stimulus Positive Regulation Of Multicellular Organism Growth Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process Regulation Of Hindgut Contraction Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Fatty Acid Metabolic Process Negative Regulation Of Insulin Secretion Decidualization Negative Regulation Of Inflammatory Response Regulation Of Synapse Assembly
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Height ( 20881960 23563607)
Protein-protein Interactions		2 interactors: CORT GHRL
Entrez ID		2693
HPRD ID		03541
Ensembl ID		ENSG00000121853
Uniprot IDs		Q92847
PDB IDs
Enriched GO Terms of Interacting Partners?		Cortisol Secretion Negative Regulation Of Circadian Sleep/wake Cycle, REM Sleep Positive Regulation Of Growth Hormone Receptor Signaling Pathway Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Cortisol Secretion Positive Regulation Of Corticotropin Secretion Positive Regulation Of Appetite Regulation Of Corticotropin Secretion Regulation Of Growth Hormone Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Circadian Sleep/wake Cycle, REM Sleep Negative Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Growth Hormone Secretion Synaptic Transmission Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Adult Feeding Behavior Gastric Acid Secretion Regulation Of Growth Hormone Secretion Growth Hormone Secretion Negative Regulation Of Interleukin-1 Beta Production Regulation Of Circadian Sleep/wake Cycle, Sleep Cell-cell Signaling Regulation Of Response To Food Positive Regulation Of Circadian Rhythm Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Circadian Rhythm Regulation Of Appetite Regulation Of Interleukin-6 Biosynthetic Process G-protein Coupled Receptor Signaling Pathway Decidualization Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Synapse Assembly Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Interleukin-6 Production Negative Regulation Of Cytokine Biosynthetic Process Negative Regulation Of Insulin Secretion Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Negative Regulation Of Peptide Secretion Maternal Placenta Development Regulation Of Interleukin-1 Beta Production Positive Regulation Of Multicellular Organism Growth Acid Secretion Positive Regulation Of Lipid Transport Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of Synapse Assembly Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Hormone Secretion Positive Regulation Of Insulin Secretion
Tagcloud ?		aa aspergillus awamori basal broiler chicks cholesterol conversion cpu crude diets digestibility dmd dry fed feed feeding fos fructooligosaccharide hdl igf1r improves lipoprotein matter secretagogue skeletal supplementation supplemented utilization