FBXO2

Gene Name		F-box protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Cytosol SCF Ubiquitin Ligase Complex Organelle Membrane Dendritic Spine Extracellular Vesicular Exosome
	Molecular Function	Beta-amyloid Binding Glycoprotein Binding Ubiquitin-protein Transferase Activity Carbohydrate Binding
	Biological Process	Cellular Protein Modification Process Proteolysis Glycoprotein Catabolic Process Negative Regulation Of Cell Proliferation Protein Ubiquitination ER-associated Ubiquitin-dependent Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: AHSG BACE1 ITGB1 KIAA0368 SKP1 STUB1 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2L3
Entrez ID		26232
HPRD ID		06171
Ensembl ID		ENSG00000116661
Uniprot IDs		Q9UK22
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein Polyubiquitination Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Ubiquitin-protein Transferase Activity Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Protein Ubiquitination Protein K48-linked Ubiquitination Protein Modification By Small Protein Conjugation Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Protein Monoubiquitination Response To Transforming Growth Factor Beta Positive Regulation Of Protein Modification Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Transferase Activity Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Proteolysis Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Protein Metabolic Process Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Regulation Of Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway
Tagcloud ?		accumulate adaptor amyloid app box cleavage cleaving enriched facilitating glycans glycoprotein glycoproteins hippocampal hippocampi incompletely integral knock ligase mannose modulating neuron plasticity preferentially processing products secretase slices sought synapses