GAS2

Description		growth arrest specific 2
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Cytoskeleton Actin Filament Membrane
	Molecular Function	Protein Binding Microtubule Binding Actin Filament Binding
	Biological Process	Initiation Of Primordial Ovarian Follicle Growth Antral Ovarian Follicle Growth Apoptotic Process Regulation Of Cell Shape Regulation Of Notch Signaling Pathway Ovulation Regulation Of Cell Cycle Actin Crosslink Formation Basement Membrane Organization
Pathways		Caspase-mediated cleavage of cytoskeletal proteins
Drugs
Diseases
GWAS		Dialysis-related mortality ( 21546767) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483)
Interacting Genes		4 interacting genes: ACTA1 APP CAPN2 TBC1D21
Entrez ID		2620
HPRD ID		04158
Ensembl ID		ENSG00000148935
Uniprot IDs		O43903
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Exosome Cell Body Mesenchyme Migration Acetylcholine Receptor Activator Activity Membrane Raft Amyloid-beta Complex PTB Domain Binding Presynapse Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Postsynapse Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Regulation Of Interleukin-6 Production Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Response To Mechanical Stimulus Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Vesicle-mediated Transport Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Phosphatidylcholine Biosynthetic Process Calpain Complex Protein Catabolic Process At Postsynapse Regulation Of Phosphatidylcholine Biosynthetic Process Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Sperm Mitochondrial Sheath Assembly Skeletal Muscle Thin Filament Assembly Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Reproductive Process Heparan Sulfate Binding
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