IBTK

Gene Name		inhibitor of Bruton agammaglobulinemia tyrosine kinase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane
	Molecular Function	Protein Kinase Binding Protein Tyrosine Kinase Inhibitor Activity
	Biological Process	Negative Regulation Of Protein Phosphorylation Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways
Drugs
Diseases
GWAS		Corneal structure ( 23291589)
Protein-protein Interactions		5 interactors: BTK LAMTOR3 PPP1CA PRKCB PRKD1
Entrez ID		25998
HPRD ID		12105
Ensembl ID		ENSG00000005700
Uniprot IDs		Q9P2D0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Enzyme Linked Receptor Protein Signaling Pathway Response To Organic Substance Regulation Of Sequence-specific DNA Binding Transcription Factor Activity B Cell Receptor Signaling Pathway Positive Regulation Of Signal Transduction Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Response To Organic Substance Regulation Of B Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Angiogenesis Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Protein Kinase D Signaling Cellular Response To Molecule Of Fungal Origin Histone H3-T6 Phosphorylation B Cell Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Histone Deacetylase Activity Peptidyl-amino Acid Modification Apoptotic Process Cellular Response To Oxidative Stress Programmed Cell Death Protein Autophosphorylation Response To Molecule Of Fungal Origin Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Death Death Regulation Of Angiogenesis Regulation Of Signal Transduction Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Histone Deacetylase Activity Phosphate-containing Compound Metabolic Process Positive Regulation Of Deacetylase Activity Regulation Of Signaling Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Cellular Protein Modification Process Protein Phosphorylation Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of B Cell Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of Glycogen Catabolic Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell Death Histamine Secretion By Mast Cell Negative Regulation Of Transport
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