GABPA

Gene Name		GA binding protein transcription factor, alpha subunit 60kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Transcription From RNA Polymerase II Promoter Organelle Organization Mitochondrion Organization Cell Differentiation Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Organelle biogenesis and maintenance Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: APP ATF1 CREBBP EP300 GABPB1 HCFC1 MED1 PINX1 SP1 SP3
Entrez ID		2551
HPRD ID		11793
Ensembl ID		ENSG00000154727
Uniprot IDs		A8IE48 Q06546 Q8IYS3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Enucleate Erythrocyte Differentiation Positive Regulation Of Cellular Metabolic Process Megakaryocyte Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process N-terminal Peptidyl-lysine Acetylation Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Immune System Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Homeostatic Process Positive Regulation By Host Of Viral Transcription Embryonic Process Involved In Female Pregnancy Negative Regulation Of Transcription From RNA Polymerase II Promoter N-terminal Protein Amino Acid Acetylation Regulation Of Metabolic Process Erythrocyte Differentiation Histone Acetylation Erythrocyte Homeostasis Embryonic Placenta Development Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Myeloid Cell Homeostasis Monocyte Differentiation Notch Signaling Pathway
Tagcloud ?		annotation assigned bindings cistrome consensus enriched examines expresses foxa2 generates hepatic hre implying isoforms livers motifs principle ra rar rara raralpha rarb rarbeta redundant responsiveness sp1 stores tca uncovered