ZFPM2

Gene Name		zinc finger protein, FOG family member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Transcription Factor Binding RNA Polymerase II Transcription Coactivator Activity DNA Binding Transcription Corepressor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Vasculogenesis In Utero Embryonic Development Outflow Tract Septum Morphogenesis Right Ventricular Cardiac Muscle Tissue Morphogenesis Transcription, DNA-templated Gonadal Mesoderm Development Blood Coagulation Lung Development Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Organ Development Ventricular Septum Morphogenesis Negative Regulation Of Cell Death Positive Regulation Of Male Gonad Development Negative Regulation Of Female Gonad Development
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Glaucoma (primary open-angle) ( 22570617) Platelet counts ( 22139419) Sudden cardiac arrest ( 21658281) Vascular endothelial growth factor levels ( 21757650)
Protein-protein Interactions		10 interactors: CTBP1 CTBP2 EP300 GATA1 GATA3 GATA4 IL32 ITSN1 STAT3 UBQLN4
Entrez ID		23414
HPRD ID		04737
Ensembl ID		ENSG00000169946
Uniprot IDs		Q8WW38 Q9NPQ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Response To Estrogen Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Binding Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Positive Regulation Of Binding Positive Regulation Of Cellular Biosynthetic Process Cardiac Right Ventricle Morphogenesis Response To Hormone White Fat Cell Differentiation Regulation Of Signal Transduction Response To Steroid Hormone Male Gonad Development Cellular Response To Organic Substance Regulation Of Transcription Regulatory Region DNA Binding Viral Genome Replication Regulation Of Signaling Viral Process Male Sex Differentiation RNA Metabolic Process Heart Valve Morphogenesis Positive Regulation Of Signal Transduction Embryonic Hemopoiesis Heart Valve Development Cell Differentiation Gonad Development Development Of Primary Sexual Characteristics Gene Expression Cellular Macromolecule Biosynthetic Process Anatomical Structure Morphogenesis Macromolecule Biosynthetic Process Sex Differentiation Response To Organic Substance Regulation Of Protein Deacetylation
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