HIC2

Gene Name		hypermethylated in cancer 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane
	Molecular Function	DNA Binding Protein C-terminus Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Mean corpuscular volume ( 20139978) Systemic lupus erythematosus ( 19838193)
Protein-protein Interactions		4 interactors: APP CCNT1 HIC1 PDK2
Entrez ID		23119
HPRD ID		07412
Ensembl ID		ENSG00000169635
Uniprot IDs		Q96JB3
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Surface Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Cell Death Death Intrinsic Apoptotic Signaling Pathway Collateral Sprouting In Absence Of Injury Protein Phosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Phosphorus Metabolic Process Axon Choice Point Recognition Apoptotic Signaling Pathway Neuron Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Phosphorylation Response To Oxidative Stress Regulation Of Acyl-CoA Biosynthetic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Signal Transduction Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Signal Transduction By P53 Class Mediator Cellular Copper Ion Homeostasis Ion Homeostasis Signaling Cell Communication Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Protein Kinase Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Stimulus RNA Polyadenylation Neuron Recognition Cellular Response To Nutrient Regulation Of Kinase Activity Phosphate-containing Compound Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Gluconeogenesis Chemical Homeostasis Ionotropic Glutamate Receptor Signaling Pathway Regulation Of Signal Transduction By P53 Class Mediator
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