SCAP

Gene Name		SREBF chaperone
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Protein Complex
	Molecular Function	Protein Binding Cholesterol Binding Protein Complex Binding Unfolded Protein Binding
	Biological Process	Response To Hypoxia Aging Cholesterol Metabolic Process Response To Insulin SREBP Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Small Molecule Metabolic Process Negative Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) Metabolism of lipids and lipoproteins
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: INSIG1 INSIG2 PGRMC1 SEC24B SREBF2
Entrez ID		22937
HPRD ID		03300
Ensembl ID		ENSG00000114650
Uniprot IDs		F8W921 Q12770
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cargo Loading Into COPII-coated Vesicle Inner Ear Morphogenesis Cholesterol Metabolic Process Ear Morphogenesis Sterol Metabolic Process Cranial Suture Morphogenesis Negative Regulation Of Fatty Acid Biosynthetic Process SREBP Signaling Pathway Response To Sterol Depletion Craniofacial Suture Morphogenesis Regulation Of ER To Golgi Vesicle-mediated Transport Inner Ear Development Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Fatty Acid Metabolic Process Ear Development Negative Regulation Of Steroid Metabolic Process Middle Ear Morphogenesis Steroid Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Cholesterol Biosynthetic Process Embryonic Organ Morphogenesis Alcohol Metabolic Process Sterol Biosynthetic Process Negative Regulation Of Lipid Biosynthetic Process Embryonic Organ Development Regulation Of Steroid Biosynthetic Process Negative Regulation Of Lipid Metabolic Process Regulation Of Fatty Acid Metabolic Process Sensory Organ Development Triglyceride Metabolic Process Regulation Of Steroid Metabolic Process Embryonic Morphogenesis Neutral Lipid Metabolic Process ER-nucleus Signaling Pathway Palate Development Steroid Biosynthetic Process Bone Morphogenesis Regulation Of Lipid Biosynthetic Process Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Small Molecule Metabolic Process Anatomical Structure Morphogenesis Negative Regulation Of Cargo Loading Into COPII-coated Vesicle Cellular Lipid Metabolic Process Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Cochlear Nucleus Development Bone Development Negative Regulation Of Cholesterol Efflux Embryo Development Pulmonary Artery Morphogenesis
Tagcloud ?		acanthosis acuminatum atypia buttock coincidental cuboidal dense dermis endophytic epidermis hyperkeratosis hyperkeratotic infiltrate keratotic koilocytotic lined nevus ns overlying papillae papillary papilliferum papillomatosis plasmacytic probes sebaceus stroma syringocystadenoma verrucous