RUFY3

Name	RUN and FYVE domain containing 3
Structure	No pdb structure
Interactors	7 interactors: ABI3 APP ARL8B CAPN3 DSCAM RAB33A UNC119
GO Annotations	Cellular Component	Cytoplasm Lysosome Cytosol Endomembrane System Membrane Lamellipodium Filopodium Axon Dendrite Growth Cone Endolysosome Cell Projection Neuronal Cell Body Perikaryon Anchoring Junction
	Molecular Function	Protein Binding Dynactin Binding
	Biological Process	Actin Filament Organization Nervous System Development Cell Differentiation Positive Regulation Of Cell Migration Positive Regulation Of Axon Extension Regulation Of Axonogenesis Negative Regulation Of Axonogenesis Positive Regulation Of Intracellular Protein Transport Regulation Of Establishment Of Cell Polarity Positive Regulation Of Retrograde Axon Cargo Transport
GWAS	No GWAS studies recorded
Entrez ID	22902
HPRD ID	15251
Ensembl ID	ENSG00000018189
Uniprot IDs	B4DG59 B4DKC2 Q7L099
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Amyloid-beta Complex Cell Projection Morphogenesis Dendritic Shaft Axon Positive Regulation Of Phosphate Metabolic Process Growth Cone Lamellipodium Trans-synaptic Signaling Chemical Synaptic Transmission Regulation Of Response To Calcium Ion Regulation Of Developmental Growth Amylin Binding Positive Regulation Of Toll Signaling Pathway Neuron Recognition Synaptic Signaling Synapse Synapse Organization Calcium-dependent Self Proteolysis Spindle Midzone Antigen Processing And Presentation Following Phagocytosis Antigen Processing And Presentation Of Polysaccharide Antigen Via MHC Class II Viral Exocytosis Axo-dendritic Transport Acetylcholine Receptor Activator Activity Lipoprotein Particle Cell Junction Organization Positive Regulation Of Protein Import Ligase Regulator Activity Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Negative Regulation Of Caveolin-mediated Endocytosis Antigen Processing And Presentation Endosome To Lysosome Transport Of Low-density Lipoprotein Particle PTB Domain Binding Regulation Of Phosphorus Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Cell Recognition Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Calcium Ion Regulated Lysosome Exocytosis Protein Localization To Early Endosome Cell-cell Signaling Regulation Of Growth