CASC3

Gene Name		cancer susceptibility candidate 3
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Gene Ontology Annotations	Cellular Component	Cytosol Nuclear Speck Ribonucleoprotein Complex Exon-exon Junction Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Processing Regulation Of Translation Biological_process Intracellular MRNA Localization RNA Splicing Gene Expression MRNA Transport
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CDK6 EIF4A3 GRB2 STAU1
Entrez ID		22794
HPRD ID		16225
Ensembl ID		ENSG00000108349
Uniprot IDs		B4DKR6 O15234
PDB IDs		2HYI 2J0Q 2J0S 2J0U 2XB2 3EX7
Enriched GO Terms of Interacting Partners?		Cell Dedifferentiation RNA Localization Positive Regulation By Virus Of Viral Protein Levels In Host Cell
Tagcloud ?		appearance bodies core correlate correlates cytoplasm cytoplasmic deregulation determining disassembly eif4aiii ejc exon fate foci granules junction loaded localizes magoh mln51 movements onto overexpressed overexpressing rbm8a spliced unlike y14