FGD1

Gene Name		FYVE, RhoGEF and PH domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Lamellipodium
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity Small GTPase Binding Metal Ion Binding
	Biological Process	Cytoskeleton Organization Signal Transduction Small GTPase Mediated Signal Transduction Multicellular Organismal Development Regulation Of Cell Shape Organ Morphogenesis Actin Cytoskeleton Organization Positive Regulation Of Rho GTPase Activity Positive Regulation Of Apoptotic Process Regulation Of Cdc42 GTPase Activity Positive Regulation Of GTPase Activity Filopodium Assembly Neurotrophin TRK Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Apoptotic Signaling Pathway
Pathways		Rho GTPase cycle Signaling by GPCR GPCR downstream signaling Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE Signaling by Rho GTPases NRAGE signals death through JNK G alpha (12/13) signalling events p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: AOC1 CDC42 CTTN ELMO1
Entrez ID		2245
HPRD ID		02373
Ensembl ID		ENSG00000102302
Uniprot IDs		P98174
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Organization Actin Filament-based Process Adherens Junction Organization Endocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Response To Copper Ion Starvation Cellular Response To Azide Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Hair Follicle Cell Proliferation Cytoskeleton Organization Cell-cell Junction Organization Actin Filament Branching Submandibular Salivary Gland Formation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Phagocytosis Fc Receptor Signaling Pathway Cellular Response To Heparin Immune Response-activating Cell Surface Receptor Signaling Pathway Vesicle-mediated Transport Cell Projection Assembly Response To Heparin Establishment Of Golgi Localization Cellular Response To Copper Ion Actin Filament Organization Movement Of Cell Or Subcellular Component Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Metalloenzyme Activity Regulation Of Protein Complex Assembly Dendritic Spine Maintenance Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Histamine Regulation Of Protein Heterodimerization Activity Keratinocyte Development Substrate-dependent Cell Migration, Cell Extension Regulation Of Synapse Structural Plasticity Response To Histamine Transport Positive Regulation Of Pseudopodium Assembly Nuclear Migration Cardiac Conduction System Development Phagocytosis, Engulfment Immune Response-regulating Signaling Pathway Regulation Of Cell Morphogenesis Golgi Localization Regulation Of Cell Projection Organization
Tagcloud ?		apo bend butterfly catalysis charged citrate coenzyme competitive crystallography facilitates flavin g6p helps identifies isoalloxazine microorganisms moiety mycobacteria nitroimidazopyran occupies packs persistence phosphate pocket prodrug replicating resolutions shared