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Gene Name
endoglin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Nucleoplasm
Cytoplasm
Focal Adhesion
External Side Of Plasma Membrane
Cell Surface
Receptor Complex
Transforming Growth Factor Beta Receptor Homodimeric Complex
Endothelial Microparticle
Molecular Function
Transmembrane Signaling Receptor Activity
Transforming Growth Factor Beta-activated Receptor Activity
Transforming Growth Factor Beta Receptor, Cytoplasmic Mediator Activity
Type II Transforming Growth Factor Beta Receptor Binding
Protein Binding
Galactose Binding
Glycosaminoglycan Binding
Type I Transforming Growth Factor Beta Receptor Binding
BMP Binding
Protein Homodimerization Activity
Activin Binding
Transforming Growth Factor Beta Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chronological Cell Aging
Patterning Of Blood Vessels
Vasculogenesis
Response To Hypoxia
Positive Regulation Of Protein Phosphorylation
Negative Regulation Of Endothelial Cell Proliferation
Heart Looping
Positive Regulation Of Systemic Arterial Blood Pressure
Cell Migration Involved In Endocardial Cushion Formation
Regulation Of Transcription, DNA-templated
Cell Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Gene Expression
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Cell Migration
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Central Nervous System Vasculogenesis
Extracellular Matrix Disassembly
Regulation Of Cell Adhesion
Negative Regulation Of Cell Migration
BMP Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of BMP Signaling Pathway
Negative Regulation Of Protein Autophosphorylation
Response To Corticosteroid
Positive Regulation Of Collagen Biosynthetic Process
Intracellular Signal Transduction
Response To Statin
Wound Healing
Regulation Of Cell Proliferation
Regulation Of Phosphorylation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Smooth Muscle Tissue Development
Artery Morphogenesis
Venous Blood Vessel Morphogenesis
Cell Motility
Negative Regulation Of Nitric-oxide Synthase Activity
Cell Chemotaxis
Bone Development
Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Extracellular Matrix Constituent Secretion
Detection Of Hypoxia
Cellular Response To Mechanical Stimulus
Response To Transforming Growth Factor Beta
Pathways
Drugs
Diseases
GWAS
Metabolic syndrome (
20694148
)
Protein-protein Interactions
12 interactors:
ACVR1
ACVR2A
BMP2
BMP7
INHBA
TCTEX1D4
TGFB1
TGFB2
TGFB3
TGFBR1
TGFBR2
TGFBR3
Entrez ID
2022
HPRD ID
00565
Ensembl ID
ENSG00000106991
Uniprot IDs
B7Z6Y5
F5GX88
P17813
Q5T9B9
Q96CG0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Pathway-restricted SMAD Protein Phosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Ossification
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Bone Mineralization
Positive Regulation Of Biomineral Tissue Development
Mesenchymal Cell Development
Positive Regulation Of Phosphorylation
Mesenchymal Cell Differentiation
Epithelial To Mesenchymal Transition
Regulation Of Epithelial To Mesenchymal Transition
SMAD Protein Signal Transduction
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Protein Modification Process
Regulation Of Cell Differentiation
Cellular Response To Growth Factor Stimulus
Organ Morphogenesis
Response To Growth Factor
Regulation Of Bone Mineralization
Regulation Of Protein Phosphorylation
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cell Proliferation
Embryo Development
Regulation Of Ossification
Cellular Response To Organic Substance
Mesenchyme Development
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of Phosphorylation
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Stem Cell Development
Response To Lipid
Growth
Positive Regulation Of Cell Differentiation
Gland Development
Response To Organic Cyclic Compound
Regulation Of Phosphorus Metabolic Process
Anatomical Structure Morphogenesis
Skeletal System Development
Stem Cell Differentiation
Sensory Organ Development
Response To Organic Substance
Tissue Development
Tissue Morphogenesis
Regulation Of Signal Transduction
Tagcloud
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actualization
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craniocorpography
ekg
electrolytes
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flunarizin
holter
hypokinesia
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overstrain
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saving
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sickness
spo
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telemetric
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