STT3B

Name	STT3 oligosaccharyltransferase complex catalytic subunit B
Structure
Novel Interactors	10 novel interactors: AADAT CAMLG CYP51A1 DDR2 EIF4H GNMT OXSR1 SATB1 SMARCC1 XYLB
Interactors	2 interactors: FILNC1 INCA1
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Oligosaccharyltransferase Complex Membrane Protein-containing Complex Oligosaccharyltransferase Complex B
	Molecular Function	Oligosaccharyl Transferase Activity Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Metal Ion Binding
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation Glycoprotein Catabolic Process Response To Unfolded Protein Protein N-linked Glycosylation Via Asparagine ERAD Pathway Post-translational Protein Modification
Pathways	Asparagine N-linked glycosylation Maturation of spike protein Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition PD-L1(CD274) glycosylation and translocation to plasma membrane
GWAS	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134 ) Diabetic retinopathy in type 2 diabetes ( 33607655 ) Periodontal disease-related phenotype (Socransky) ( 24347629 ) Urate levels ( 31578528 )
Entrez ID	201595
HPRD ID	12268
Ensembl ID	ENSG00000163527
Uniprot IDs	Q8TCJ2
PDB IDs	6S7T
GO Terms Enriched among Interactors ?	Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Sterol 14-demethylase Activity Cholesterol Biosynthetic Process Via 24,25-dihydrolanosterol Xylulose Catabolic Process D-xylulokinase Activity Aspartate Family Amino Acid Metabolic Process Glycine N-methyltransferase Activity Methionine-glyoxylate Transaminase Activity Glycine:2-oxoglutarate Aminotransferase Activity 2-aminoadipate Transaminase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Hepatic Stellate Cell Proliferation Protein Tyrosine Kinase Collagen Receptor Activity RNA Strand-exchange Activity Eukaryotic Translation Initiation Factor 4F Complex Assembly Xylulose Metabolic Process Sarcosine Metabolic Process S-adenosylhomocysteine Metabolic Process Kynurenine-glyoxylate Transaminase Activity GET Complex Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Phosphorylation Regulation Of Fibroblast Proliferation D-xylose Metabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine