STT3B and XYLB

		STT3B	XYLB
Description		STT3 oligosaccharyltransferase complex catalytic subunit B	xylulokinase
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Oligosaccharyltransferase Complex Membrane Protein-containing Complex Oligosaccharyltransferase Complex B	Cytosol
	Molecular Function	Oligosaccharyl Transferase Activity Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Metal Ion Binding	Nucleotide Binding D-xylulokinase Activity ATP Binding Kinase Activity Transferase Activity
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation Glycoprotein Catabolic Process Response To Unfolded Protein Protein N-linked Glycosylation Via Asparagine ERAD Pathway Post-translational Protein Modification	Carbohydrate Metabolic Process Xylulose Metabolic Process Xylulose Catabolic Process Generation Of Precursor Metabolites And Energy D-glucuronate Catabolic Process To D-xylulose 5-phosphate D-xylose Metabolic Process Carbohydrate Phosphorylation
Pathways		Asparagine N-linked glycosylation Maturation of spike protein Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition PD-L1(CD274) glycosylation and translocation to plasma membrane	Formation of xylulose-5-phosphate
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Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Diabetic retinopathy in type 2 diabetes ( 33607655) Periodontal disease-related phenotype (Socransky) ( 24347629) Urate levels ( 31578528)	Bitter alcoholic beverage consumption ( 31046077) Estimated glomerular filtration rate ( 30604766 31015462) Hippocampal volume ( 29860282) Major depressive disorder ( 29317602) P wave duration ( 24850809) Urinary metabolites ( 26352407)
Interacting Genes		2 interacting genes: FILNC1 INCA1
Entrez ID		201595	9942
HPRD ID		12268	06812
Ensembl ID		ENSG00000163527	ENSG00000093217
Uniprot IDs		Q8TCJ2	C9J0N9 O75191
PDB IDs		6S7T	4BC2 4BC3 4BC4 4BC5
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Sterol 14-demethylase Activity Cholesterol Biosynthetic Process Via 24,25-dihydrolanosterol Xylulose Catabolic Process D-xylulokinase Activity Aspartate Family Amino Acid Metabolic Process Glycine N-methyltransferase Activity Methionine-glyoxylate Transaminase Activity Glycine:2-oxoglutarate Aminotransferase Activity 2-aminoadipate Transaminase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Hepatic Stellate Cell Proliferation Protein Tyrosine Kinase Collagen Receptor Activity RNA Strand-exchange Activity Eukaryotic Translation Initiation Factor 4F Complex Assembly Xylulose Metabolic Process Sarcosine Metabolic Process S-adenosylhomocysteine Metabolic Process Kynurenine-glyoxylate Transaminase Activity GET Complex Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Phosphorylation Regulation Of Fibroblast Proliferation D-xylose Metabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine	PAM Complex, Tim23 Associated Import Motor Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Oligosaccharyl Transferase Activity Oligosaccharyltransferase Complex B TIM23 Mitochondrial Import Inner Membrane Translocase Complex Adenyl-nucleotide Exchange Factor Activity Oligosaccharyltransferase Complex Protein Import Into Mitochondrial Matrix Protein N-linked Glycosylation Via Asparagine Glycoprotein Catabolic Process Protein Localization To Mitochondrion
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