STT3B and EIF4H

		STT3B	EIF4H
Description		STT3 oligosaccharyltransferase complex catalytic subunit B	eukaryotic translation initiation factor 4H
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Oligosaccharyltransferase Complex Membrane Protein-containing Complex Oligosaccharyltransferase Complex B	Cytoplasm Cytosol Membrane Eukaryotic Translation Initiation Factor 4F Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Oligosaccharyl Transferase Activity Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Metal Ion Binding	Nucleic Acid Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding RNA Strand Annealing Activity RNA Strand-exchange Activity Ribosomal Small Subunit Binding Cadherin Binding
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation Glycoprotein Catabolic Process Response To Unfolded Protein Protein N-linked Glycosylation Via Asparagine ERAD Pathway Post-translational Protein Modification	Formation Of Translation Preinitiation Complex Translation Translational Initiation Regulation Of Translational Initiation Sexual Reproduction Developmental Growth Eukaryotic Translation Initiation Factor 4F Complex Assembly
Pathways		Asparagine N-linked glycosylation Maturation of spike protein Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition PD-L1(CD274) glycosylation and translocation to plasma membrane	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Diabetic retinopathy in type 2 diabetes ( 33607655) Periodontal disease-related phenotype (Socransky) ( 24347629) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: FILNC1 INCA1	8 interacting genes: C11orf68 CEBPA DDIT4L DLG3 FBXO17 LNX1 PICK1 SPG21
Entrez ID		201595	7458
HPRD ID		12268	11940
Ensembl ID		ENSG00000163527	ENSG00000106682
Uniprot IDs		Q8TCJ2	Q15056
PDB IDs		6S7T
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Sterol 14-demethylase Activity Cholesterol Biosynthetic Process Via 24,25-dihydrolanosterol Xylulose Catabolic Process D-xylulokinase Activity Aspartate Family Amino Acid Metabolic Process Glycine N-methyltransferase Activity Methionine-glyoxylate Transaminase Activity Glycine:2-oxoglutarate Aminotransferase Activity 2-aminoadipate Transaminase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Hepatic Stellate Cell Proliferation Protein Tyrosine Kinase Collagen Receptor Activity RNA Strand-exchange Activity Eukaryotic Translation Initiation Factor 4F Complex Assembly Xylulose Metabolic Process Sarcosine Metabolic Process S-adenosylhomocysteine Metabolic Process Kynurenine-glyoxylate Transaminase Activity GET Complex Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Phosphorylation Regulation Of Fibroblast Proliferation D-xylose Metabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?