SERPINB1

Gene Name		serpin peptidase inhibitor, clade B (ovalbumin), member 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Membrane Extracellular Vesicular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Negative Regulation Of Endopeptidase Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: ELANE PRTN3 XPO1
Entrez ID		1992
HPRD ID		00555
Ensembl ID		ENSG00000021355
Uniprot IDs		P30740
PDB IDs		4GA7
Enriched GO Terms of Interacting Partners?		Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Neutrophil Mediated Killing Of Fungus Ribosomal Small Subunit Export From Nucleus Negative Regulation Of Chemokine Biosynthetic Process Negative Regulation Of Interleukin-8 Biosynthetic Process Response To Yeast Mature Conventional Dendritic Cell Differentiation Ribosomal Large Subunit Export From Nucleus Positive Regulation Of Interleukin-8 Biosynthetic Process Killing By Host Of Symbiont Cells Ribosomal Subunit Export From Nucleus Acute Inflammatory Response To Antigenic Stimulus Regulation Of Interleukin-8 Biosynthetic Process Negative Regulation Of Phagocytosis Negative Regulation Of Interleukin-8 Production Neutrophil Mediated Immunity Killing Of Cells Of Other Organism Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Export From Nucleus Negative Regulation Of Growth Of Symbiont In Host Negative Regulation Of Chemotaxis Defense Response To Fungus Intracellular Transport Of Virus Positive Regulation Of Cell Proliferation Positive Regulation Of Interleukin-8 Production Protein Export From Nucleus Interaction With Symbiont Inflammatory Response To Antigenic Stimulus Leukocyte Mediated Cytotoxicity Regulation Of Centrosome Duplication Negative Regulation Of Cytokine Biosynthetic Process Dendritic Cell Differentiation Response To Fungus Regulation Of Centrosome Cycle Negative Regulation Of Endocytosis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Chemokine Production Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Phagocytosis Positive Regulation Of Cytokine Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Acute Inflammatory Response Regulation Of Cell Proliferation
Tagcloud ?		a431 a431cells allowing annotation apoptotic components cytochrome cytoskeletal dnaaseii egf epidermoid evenly exploited modeled networks overexpress proteome proteomic proteomics signalling split stream sub suppressors tp53 trigger triggering undergo unlikely