DCP1B

Gene Name		decapping mRNA 1B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus Cytoplasm Cytosol Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	RNA 7-methylguanosine Cap Binding MRNA Binding Protein Binding Hydrolase Activity Enzyme Regulator Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Gene Expression Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Regulation Of Catalytic Activity
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Obesity-related traits ( 23251661) Response to gemcitabine in pancreatic cancer ( 22142827)
Protein-protein Interactions		8 interactors: DCP2 EDC3 EXOSC6 LSM8 SMAD4 UPF2 XRN1 ZFP36
Entrez ID		196513
HPRD ID		13124
Ensembl ID		ENSG00000151065
Uniprot IDs		Q8IZD4
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Catabolic Process RNA Catabolic Process MRNA Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Aromatic Compound Catabolic Process Cellular Macromolecule Catabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone MRNA Catabolic Process Cellular Nitrogen Compound Metabolic Process Catabolic Process Nitrogen Compound Metabolic Process Histone MRNA Metabolic Process Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nephrogenic Mesenchyme Morphogenesis RRNA Metabolic Process Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Cellular Metabolic Process Endocardial Cell Differentiation Nuclear MRNA Surveillance Formation Of Anatomical Boundary Negative Regulation Of Translation Involved In Gene Silencing By MiRNA DNA Deamination Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis RNA Surveillance Endothelial Cell Activation Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Valve Formation Sebaceous Gland Development 3'-UTR-mediated MRNA Stabilization Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Somite Rostral/caudal Axis Specification Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation RRNA Catabolic Process Brainstem Development SMAD Protein Complex Assembly RNA Destabilization Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Canal Development Regulation Of Hair Follicle Development Nucleic Acid Phosphodiester Bond Hydrolysis
Tagcloud ?		atxn2 bid ccnf cdkn1a cntn4 dysregulations granule granules haploinsufficiency hnrnpa1 hnrnpa2b1 immunoblots inca1 mapt noteworthy nucleator plin4 pnpla2 prioritized smn tardbp tbc1d24 tia tia1 tial1 tprkb translocate upregulations wdfy1