ADRB3

Gene Name		adrenoceptor beta 3
Image
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Beta-adrenergic Receptor Activity Protein Binding Beta3-adrenergic Receptor Activity Beta-3 Adrenergic Receptor Binding Protein Homodimerization Activity Epinephrine Binding Norepinephrine Binding
	Biological Process	Diet Induced Thermogenesis Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Carbohydrate Metabolic Process Generation Of Precursor Metabolites And Energy Energy Reserve Metabolic Process Receptor-mediated Endocytosis G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Aging Response To Cold Heat Generation Negative Regulation Of Multicellular Organism Growth Eating Behavior Positive Regulation Of MAPK Cascade Response To Antibiotic Brown Fat Cell Differentiation Adrenergic Receptor Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Adrenoceptors Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Norepinephrine Propranolol Isoproterenol Arbutamine Fenoterol Ephedra Clenbuterol Droxidopa Bopindolol Bupranolol Mirabegron
Diseases
GWAS
Protein-protein Interactions		3 interactors: ADRB2 GNAS SRC
Entrez ID		155
HPRD ID		00188
Ensembl ID		ENSG00000188778
Uniprot IDs		A8KAG8 P13945
PDB IDs		2CDW
Enriched GO Terms of Interacting Partners?		Tissue Homeostasis Multicellular Organismal Homeostasis Adrenergic Receptor Signaling Pathway Negative Regulation Of Multicellular Organism Growth Activation Of Adenylate Cyclase Activity Bone Resorption Positive Regulation Of Adenylate Cyclase Activity Cellular Response To Fatty Acid Positive Regulation Of Lyase Activity Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Bone Remodeling Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Response To Fatty Acid Positive Regulation Of Cyclic Nucleotide Metabolic Process Negative Regulation Of Developmental Growth Regulation Of CAMP Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Ossification Regulation Of Multicellular Organism Growth Regulation Of CAMP Metabolic Process Tissue Remodeling Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Protein Binding Post-embryonic Body Morphogenesis Positive Regulation Of Signal Transduction Cellular Response To Acid Chemical Platelet Activation Homeostatic Process Regulation Of Ossification Cellular Response To Progesterone Stimulus Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Regulation Of Phosphorus Metabolic Process Bone Development Positive Regulation Of Catalytic Activity Negative Regulation Of Growth Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Binding Activation Of Protein Kinase Activity Regulation Of Intracellular Signal Transduction Regulation Of Developmental Growth Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Blood Circulation Cellular Response To Peptide
Tagcloud ?		adiposity adjusted adra2b apai bsmi circumference considerable covariates dimensionality educational esr1 genotype hip lepr logistic menopause multifactor obesity overweight postmenopausal sign tc tt ucp1 ucp2 unadjusted vdr vietnamese waist