CYBB

Gene Name		cytochrome b-245, beta polypeptide
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Gene Ontology Annotations	Cellular Component	Mitochondrion Rough Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Dendrite Phagocytic Vesicle Membrane NADPH Oxidase Complex Neuronal Cell Body
	Molecular Function	Voltage-gated Ion Channel Activity Protein Binding Electron Carrier Activity Superoxide-generating NADPH Oxidase Activity Heme Binding Metal Ion Binding Protein Heterodimerization Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Superoxide Metabolic Process Ion Transport Inflammatory Response Response To Nutrient Regulation Of Ion Transmembrane Transport Response To Drug Superoxide Anion Generation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Innate Immune Response Respiratory Burst Vascular Endothelial Growth Factor Receptor Signaling Pathway Hydrogen Peroxide Biosynthetic Process Interaction With Host Oxidation-reduction Process Phagosome Maturation
Pathways		Signaling by VEGF Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation VEGFA-VEGFR2 Pathway Cross-presentation of particulate exogenous antigens (phagosomes) Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: ACTG1 CYBA IQGAP1 NCF2 NCF4 RAC1
Entrez ID		1536
HPRD ID		02382
Ensembl ID		ENSG00000165168
Uniprot IDs		F5GWD2 P04839
PDB IDs		3A1F
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Phagosome Maturation Interaction With Host Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Immune Response Respiratory Burst Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Cell Surface Receptor Signaling Pathway Superoxide Anion Generation Antigen Processing And Presentation Of Peptide Antigen Innate Immune Response Antigen Processing And Presentation Positive Regulation Of Blood Pressure Immune System Process Superoxide Metabolic Process Signal Transduction Defense Response Signaling Cell Communication Organelle Organization Ephrin Receptor Signaling Pathway Negative Regulation Of Glomerular Filtration By Angiotensin Smooth Muscle Hypertrophy Regulation Of Body Fluid Levels Reactive Oxygen Species Metabolic Process Neuron Projection Morphogenesis Response To Glucose Response To External Stimulus Cellular Response To Stimulus Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Cellular Response To Organic Substance Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Engulfment Of Apoptotic Cell Regulation Of Renal Output By Angiotensin Neuron Projection Development Regulation Of Blood Pressure Cell Projection Morphogenesis Tissue Homeostasis Cell Part Morphogenesis Response To Carbohydrate Mast Cell Chemotaxis Platelet Activation Epithelial Cell Development Cell-cell Junction Organization
Tagcloud ?		allelic candidiasis definition designation errors ifngr1 ifngr2 il12b il12rb1 immunological impair inborn intramacrophagic irf8 isg15 mendelian msmd mycobacteria nemo overt parasites penetrance perhaps physiologically predisposition recapitulate salmonellosis virulent weakly