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IL23R
Gene Name
interleukin 23 receptor
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Receptor Complex
Interleukin-23 Receptor Complex
Molecular Function
Interleukin-12 Receptor Binding
Interleukin-23 Binding
Interleukin-23 Receptor Activity
Biological Process
Positive Regulation Of T Cell Mediated Cytotoxicity
Positive Regulation Of Defense Response To Virus By Host
Positive Regulation Of T-helper 1 Type Immune Response
Inflammatory Response
Positive Regulation Of Activation Of JAK2 Kinase Activity
Response To Lipopolysaccharide
Negative Regulation Of Interleukin-10 Production
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-17 Production
Positive Regulation Of Natural Killer Cell Proliferation
Response To Interferon-gamma
Interleukin-23-mediated Signaling Pathway
Positive Regulation Of T Cell Proliferation
Positive Regulation Of Activated T Cell Proliferation
Regulation Of Tyrosine Phosphorylation Of Stat1 Protein
Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein
Positive Regulation Of Tyrosine Phosphorylation Of Stat4 Protein
Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein
Positive Regulation Of Memory T Cell Differentiation
Positive Regulation Of Osteoclast Differentiation
Defense Response To Gram-negative Bacterium
Positive Regulation Of NK T Cell Activation
Positive Regulation Of T-helper 17 Type Immune Response
Positive Regulation Of T-helper 17 Cell Lineage Commitment
Pathways
Drugs
Diseases
GWAS
Ankylosing spondylitis (
21743469
20062062
)
Behcet's disease (
20622878
20622879
)
Crohn's disease (
18587394
20570966
22936669
22412388
17435756
17554300
21102463
17447842
22293688
17804789
)
Inflammatory bowel disease (
18758464
23128233
17068223
)
Leprosy (
22019778
)
Psoriasis (
20953190
19169254
)
Ulcerative colitis (
19915572
20228799
21297633
19122664
)
Protein-protein Interactions
5 interactors:
C1D
IL12RB1
IL23A
JAK2
STAT3
Entrez ID
149233
HPRD ID
16249
Ensembl ID
ENSG00000162594
Uniprot IDs
Q5VWK5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Interleukin-12-mediated Signaling Pathway
Positive Regulation Of T-helper 17 Cell Lineage Commitment
Response To Interleukin-12
Positive Regulation Of Memory T Cell Differentiation
Positive Regulation Of T-helper 17 Type Immune Response
Regulation Of Memory T Cell Differentiation
Positive Regulation Of T-helper 1 Type Immune Response
Positive Regulation Of Defense Response To Virus By Host
Positive Regulation Of Cell Fate Commitment
Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Positive Regulation Of Activated T Cell Proliferation
Growth Hormone Receptor Signaling Pathway
Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein
Cellular Response To Growth Hormone Stimulus
Positive Regulation Of T-helper Cell Differentiation
Regulation Of Defense Response To Virus By Host
Regulation Of Tyrosine Phosphorylation Of Stat3 Protein
Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Regulation Of Cell Fate Commitment
Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation
Positive Regulation Of Cell Activation
Regulation Of T-helper Cell Differentiation
Regulation Of Activated T Cell Proliferation
Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Response To Growth Hormone
Positive Regulation Of Cytokine Production
Positive Regulation Of Alpha-beta T Cell Differentiation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Positive Regulation Of Interferon-gamma Production
JAK-STAT Cascade
Defense Response
Positive Regulation Of Tumor Necrosis Factor Production
Cytokine-mediated Signaling Pathway
Positive Regulation Of JAK-STAT Cascade
Regulation Of Cell Proliferation
Regulation Of Cell Activation
Regulation Of Cell Differentiation
Regulation Of Cytokine Production
Regulation Of Defense Response To Virus
Positive Regulation Of T Cell Proliferation
Positive Regulation Of T Cell Differentiation
Positive Regulation Of T Cell Mediated Cytotoxicity
Regulation Of Interferon-gamma Production
Regulation Of T Cell Mediated Cytotoxicity
Cellular Response To Cytokine Stimulus
Regulation Of JAK-STAT Cascade
Regulation Of Cell Migration
Tagcloud
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1p36
21q21
bowel
c13orf31
colitis
crohn
danish
epistasis
epistatic
il10
latvia
latvian
lithuania
lithuanian
maps
mst1
nkx2
northeastern
ormdl3
ptpn22
rs2476601
rs3764147
snp
snps
strongest
subphenotype
tagging
uc
ulcerative