CSF1

Gene Name		colony stimulating factor 1 (macrophage)
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Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane Receptor Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Cytokine Activity Macrophage Colony-stimulating Factor Receptor Binding Growth Factor Activity Protein Homodimerization Activity
	Biological Process	Ossification Positive Regulation Of Cell-matrix Adhesion Osteoclast Proliferation Developmental Process Involved In Reproduction Inflammatory Response Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Macrophage Derived Foam Cell Differentiation Hemopoiesis Cell Differentiation Macrophage Differentiation Regulation Of Ossification Osteoclast Differentiation Positive Regulation Of Cell Migration Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Multicellular Organism Growth Monocyte Activation Odontogenesis Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Innate Immune Response Positive Regulation Of Macrophage Differentiation Positive Regulation Of Monocyte Differentiation Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Ras Protein Signal Transduction Homeostasis Of Number Of Cells Within A Tissue Branching Involved In Mammary Gland Duct Morphogenesis Mammary Gland Fat Development Mammary Duct Terminal End Bud Growth
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Paget's disease ( 21623375 20436471)
Protein-protein Interactions		10 interactors: CSF1R FHL3 GAB3 HLA-B NOTCH2NL PIK3R2 SGTA SLA2 SOCS1 TNF
Entrez ID		1435
HPRD ID		00388
Ensembl ID		ENSG00000184371
Uniprot IDs		P09603
PDB IDs		1HMC 3UEZ 3UF2 4ADF 4FA8
Enriched GO Terms of Interacting Partners?		Immune Response Immune System Process Regulation Of Immune Response Myeloid Leukocyte Differentiation Cytokine-mediated Signaling Pathway Macrophage Differentiation Cell Surface Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Positive Regulation Of Immune Response Regulation Of Immune System Process Defense Response Positive Regulation Of Transcription Factor Import Into Nucleus Response To Cytokine Myeloid Cell Differentiation Positive Regulation Of Chemokine Production Osteoclast Differentiation Innate Immune Response Regulation Of Kinase Activity Regulation Of Chemokine Production Cellular Response To Amino Acid Stimulus Leukocyte Differentiation Positive Regulation Of Protein Transport Positive Regulation Of Immune System Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Immune System Process Negative Regulation Of Branching Involved In Lung Morphogenesis Negative Regulation Of L-glutamate Transport Regulation Of Cellular Amino Acid Metabolic Process Cellular Response To Organic Substance Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Positive Regulation Of Cytokine Secretion Regulation Of Transcription Factor Import Into Nucleus Regulation Of JAK-STAT Cascade Positive Regulation Of Protein Import Into Nucleus Interferon-gamma-mediated Signaling Pathway Cellular Response To Organonitrogen Compound Regulation Of Interleukin-6 Production Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Macrophage Colony-stimulating Factor Signaling Pathway Response To Gold Nanoparticle Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Cellular Ketone Metabolic Process Response To Amino Acid Cellular Response To Interferon-gamma Positive Regulation Of Adaptive Immune Response
Tagcloud ?		bands constructs ddpcr encodes escape exceptions finger g401 genitourinary greatly hek293 indeed influences kidneys lesser none northern saos similarity steady tetracycline thousand transfected transfection tumorigenicity unambiguously verified wilms wt1